Repair of cellular radiation damage in space under microgravity conditions

被引：0

作者：

H. D. Pross

J. Kiefer

机构：

[1] Strahlenzentrum der Justus-Liebig-Universität,

[2] Leihgesterner Weg 217,undefined

[3] D-35392 Giessen,undefined

[4] Germany e-mail: Juergen.Kiefer@strz.uni-giessen.de Tel.: +49-641-9915300 Fax: +49-641-9915009,undefined

来源：

Radiation and Environmental Biophysics | 1999年 / 38卷

关键词：

Saccharomyces Cerevisiae; Final Analysis; Radiation Damage; Microgravity Condition; Permissive Temperature;

D O I：

暂无

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学科分类号：

摘要：

The influence of microgravity on the repair of x-ray-induced DNA double-strand breaks was studied in the temperature-conditional repair mutant rad54–3 of diploid yeast Saccharomyces cerevisiae. Cells were exposed on the ground and kept at a low temperature until microgravity conditions were achieved. In orbit, they were incubated at the permissive temperature to allow repair. Before re-entry they were again cooled down and kept at a low temperature until final analysis. The experiment, which was flown on the shuttle Atlantis on flight STS-76 (SMM-03), showed that repair of pre-formed DNA double-strand breaks in yeast is not impaired by microgravity.

引用

页码：133 / 138

页数：5