Clinical guide to fertility preservation in hematopoietic cell transplant recipients

被引：0

作者：

S Joshi

B N Savani

E J Chow

M H Gilleece

J Halter

D A Jacobsohn

J Pidala

G P Quinn

J-Y Cahn

A A Jakubowski

N R Kamani

H M Lazarus

J D Rizzo

H C Schouten

G Socie

P Stratton

M L Sorror

A B Warwick

J R Wingard

A W Loren

N S Majhail

机构：

[1] Nationwide Children’s Hospital,Department of Haematology

[2] Vanderbilt University Medical Center,Division of Hematology

[3] Fred Hutchinson Cancer Research Center,Division of Blood and Marrow Transplantation

[4] St. James’s University Hospital,Department of Health Outcomes and Behavior

[5] University Hospital Basel,Department of Hematology

[6] Children’s National Medical Center,Division of Hematologic Oncology

[7] Blood and Marrow Transplantation,Department of Pediatrics

[8] Moffitt Cancer Center,undefined

[9] Moffitt Cancer Center,undefined

[10] University Hospital,undefined

[11] Memorial Sloan-Kettering Cancer Center,undefined

[12] Center for Cancer and Blood Disorders,undefined

[13] Children’s National Medical Center,undefined

[14] Seidman Cancer Center,undefined

[15] University Hospitals Case Medical Center,undefined

[16] Center for International Blood and Marrow Transplant Research,undefined

[17] Medical College of Wisconsin,undefined

[18] University Hospital Maastricht,undefined

[19] Hopital Saint Louis,undefined

[20] Eunice Kennedy Shriver National Institute of Child Health and Human Development,undefined

[21] Uniformed Services University,undefined

[22] Bone Marrow Transplant,undefined

[23] Shands HealthCare,undefined

[24] University of Florida,undefined

[25] Perelman School of Medicine,undefined

[26] University of Pennsylvania,undefined

[27] Center for International Blood and Marrow Transplant Research,undefined

[28] National Marrow Donor Program,undefined

来源：

Bone Marrow Transplantation | 2014年 / 49卷

关键词：

hematopoietic cell transplantation; autologous; allogeneic; fertility preservation; pregnancy; assisted reproduction;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

With broadening indications, more options for hematopoietic cell transplantation (HCT) and improvement in survival, the number of long-term HCT survivors is expected to increase steadily. Infertility is a frequent problem that long-term HCT survivors and their partners face and it can negatively impact on the quality of life. The most optimal time to address fertility issues is before the onset of therapy for the underlying disease; however, fertility preservation should also be addressed before HCT in all children and patients of reproductive age, with referral to a reproductive specialist for patients interested in fertility preservation. In vitro fertilization (IVF) and embryo cryopreservation, oocyte cryopreservation and ovarian tissue banking are acceptable methods for fertility preservation in adult women/pubertal females. Sperm banking is the preferred method for adult men/pubertal males. Frequent barriers to fertility preservation in HCT recipients may include the perception of lack of time to preserve fertility given an urgency to move ahead with transplant, lack of patient–physician discussion because of several factors (for example, time constraints, lack of knowledge), inadequate access to reproductive specialists, and costs and lack of insurance coverage for fertility preservation. There is a need to raise awareness in the medical community about fertility preservation in HCT recipients.

引用

页码：477 / 484

页数：7

共 483 条

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