Spotlight on Lamotrigine in Bipolar Disorder

被引：0
作者：
David R. Goldsmith
Antona J. Wagstaff
Tim Ibbotson
Caroline M. Perry
机构：
[1] Adis International Limited,
来源：
CNS Drugs | 2004年 / 18卷
关键词：
Bipolar Disorder; Lamotrigine; Bipolar Depression; Bodyweight Gain; Valproate Semisodium;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Lamotrigine (Lamictal®), a phenyltriazine derivative, is a well established anticonvulsant agent that has shown efficacy in the prevention of mood episodes in adult patients with bipolar I disorder. The mechanism of action of the drug in patients with bipolar disorder may be related to the inhibition of sodium and calcium channels in presynaptic neurons and subsequent stabilisation of the neuronal membrane.
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页码：63 / 67
页数：4
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