ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cell-fibroblast cross-talk involved in NSCLC MultiDrug Resistance

被引:0
作者
Dania Movia
Despina Bazou
Adriele Prina-Mello
机构
[1] University of Dublin Trinity College,Department of Clinical Medicine/Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences
[2] Mater Misericordiae University Hospital,AMBER Centre
[3] CRANN Institute,undefined
[4] University of Dublin Trinity College,undefined
来源
BMC Cancer | / 19卷
关键词
3D in vitro model; Lung cancer; Inhaled drugs; ALI cultures;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 541 条
[31]  
Burke M(2013)Human lung cancer-associated fibroblasts enhance motility of non-small cell lung cancer cells in co-culture Anticancer Res 33 2001-1100
[32]  
Revelli DA(2010)Cellular bridges: routes for intercellular communication and cell migration Commun Integr Biol 3 215-213
[33]  
Gigliotti AP(2016)The relationship of transforming growth factor-β and lung cancer Int J Clin Exp Med 9 9766-8976
[34]  
Belinsky SA(2001)Transforming growth factor-beta1 level correlates with angiogenesis, tumor progression, and prognosis in patients with nonsmall cell lung carcinoma Cancer 91 964-2038
[35]  
Tessema M(1994)Transforming growth factor beta 1 as a prognostic factor in pulmonary adenocarcinoma J Clin Pathol 47 1098-1848
[36]  
Patton JS(2013)Interaction between non-small-cell lung cancer cells and fibroblasts via enhancement of TGF-beta signaling by IL-6 Lung Cancer (Amsterdam, Netherlands) 82 204-446
[37]  
Fishburn CS(2009)Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy Cancer Res 69 8967-1958
[38]  
Weers JG(2007)The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway Mol Cancer Ther 6 2029-50
[39]  
Gagnadoux F(2015)Critical contribution of MCL-1 in EMT-associated chemo-resistance in A549 non-small cell lung cancer Int J Oncol 46 1844-442
[40]  
Hureaux J(2016)3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained Sci Rep 6 19103-3114