Transcription of the vascular endothelial growth factor receptor-3 (VEGFR3) gene is regulated by the zinc finger proteins Sp1 and Sp3 and is under epigenetic controlTranscription of vascular endothelial growth factor receptor 3

被引:0
作者
Johannes Hertel
Christoph Hirche
Christoph Wissmann
Matthias P. Ebert
Michael Höcker
机构
[1] Charité University Hospital Berlin,Laboratory for Angiogenesis and Tumor Metastasis, Campus Mitte
[2] University Hospital Mannheim,Department of Medicine II
[3] University of Heidelberg,Department of Hand, Plastic, and Reconstructive Surgery, Trauma Centre Ludwigshafen, Department of Plastic and Hand Surgery
[4] University of Heidelberg,undefined
来源
Cellular Oncology | 2014年 / 37卷
关键词
VEGFR-3; FLT-4; Sp factors; GC rich element; Epigenetic regulation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:131 / 145
页数:14
相关论文
共 297 条
  • [1] Yancopoulos GD(2000)Vascular-specific growth factors and blood vessel formation Nature 407 242-248
  • [2] Davis S(1999)Vascular endothelial growth factor (VEGF) and its receptors FASEB J. 13 9-22
  • [3] Gale NW(2003)Expression of vascular endothelial growth factor (VEGF)-D and its receptor, VEGF receptor 3, as a prognostic factor in endometrial carcinoma Clin. Cancer Res. 9 1361-1369
  • [4] Rudge JS(2003)Clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in patients with nonsmall cell lung carcinoma Cancer 97 457-464
  • [5] Wiegand SJ(2003)Flt-4-positive vessel density correlates with vascular endothelial growth factor-d expression, nodal status, and prognosis in breast cancer Clin. Cancer Res. 9 5313-5317
  • [6] Holash J(2001)Lymphangiogenesis and the vascular endothelial growth factor receptor (VEGFR)-3 in gastric cancer Eur. J. Cancer 37 918-923
  • [7] Neufeld G(2003)Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma Br. J. Cancer 88 237-244
  • [8] Cohen T(2004)Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer Cancer Sci. 95 328-333
  • [9] Gengrinovitch S(2004)Expression and regulation of neuropilins and VEGF receptors by TNF-alpha in human endothelial cells J. Surg. Res. 122 249-255
  • [10] Poltorak Z(2009)Analysis of the coding regions of VEGFR3 and VEGFC in Milroy disease and other primary lymphoedemas Hum. Genet. 124 625-631