Impact of age on serum concentrations of venlafaxine and escitalopram in different CYP2D6 and CYP2C19 genotype subgroups

被引:0
作者
Ragnhild Birkeland Waade
Monica Hermann
Hanne Lewis Moe
Espen Molden
机构
[1] Diakonhjemmet Hospital,Center for Psychopharmacology
[2] University of Oslo,Department of Pharmaceutical Biosciences, School of Pharmacy
来源
European Journal of Clinical Pharmacology | 2014年 / 70卷
关键词
Elderly; Antidepressants; Pharmacokinetics; CYP450; Serum concentrations; Therapeutic drug monitoring;
D O I
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中图分类号
学科分类号
摘要
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页码:933 / 940
页数:7
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[1]  
Mulsant BH(1999)Epidemiology and diagnosis of depression in late life J Clin Psychiatry 60 9-15
[2]  
Ganguli M(1967)Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds Life Sci 6 1895-1903
[3]  
Hammer W(1969)Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapy Br Med J 4 764-768
[4]  
Sjöqvist F(2002)Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting Ther Drug Monit 24 545-553
[5]  
Alexanderson B(2009)Serum concentrations of antidepressant drugs in a naturalistic setting: compilation based on a large therapeutic drug monitoring database Ther Drug Monit 31 42-56
[6]  
Evans DAP(2008)Impact of the ultrarapid Clin Pharm Ther 83 322-327
[7]  
Sjöqvist F(1999) allele on serum concentration of escitalopram in psychiatric patients Neuropsychopharmacol 20 480-490
[8]  
Reis M(1996)O- and N-demethylation of venlafaxine Br J Clin Pharmacol 41 149-156
[9]  
Lundmark J(1993) by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants Ther Drug Monit 15 11-17
[10]  
Björk H(2003)Venlafaxine oxidation in vitro is catalysed by CYP2D6 Drug Metab Dispos 31 1255-1259