Phase II study of S-1 monotherapy in patients with previously treated, advanced non-small-cell lung cancer

被引:0
作者
M. Wada
M. Yamamoto
S. Ryuge
Y. Nagashima
N. Hayashi
S. Maki
S. Otani
K. Katono
A. Takakura
T. Yanaihara
S. Igawa
M. Yokoba
H. Mitsufuji
M. Kubota
M. Katagiri
N. Masuda
机构
[1] Kitasato University School of Medicine,Department of Respiratory Medicine
[2] Kitasato University School of Allied Health Sciences,Department of Clinical Physiology
来源
Cancer Chemotherapy and Pharmacology | 2012年 / 69卷
关键词
S-1; Non-small-cell lung cancer; Second-line chemotherapy; Phase II study; Oral cytotoxic agent; EGFR mutation;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:1005 / 1011
页数:6
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  • [1] Govindan R(2011)Phase II trial of S-1 as second-line therapy in patients with advanced non-small cell lung cancer J Thorac Oncol 6 790-795
  • [2] Morgenzstern D(2004)Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy J Clin Oncol 22 1589-1597
  • [3] Kommor MD(2009)S-1 monotherapy in patients with pretreated advanced non-small cell lung cancer Gan To Kagaku Ryoho 36 963-967
  • [4] Herbst RS(1999)Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug Clin Cancer Res 5 2000-2005
  • [5] Schaefer P(2001)Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer Br J Cancer 85 939-943
  • [6] Gandhi J(1997)Determination of S-1 (combined drug of tegafur, 5-chloro-2, 4-dihydroxypyridine and potassium oxonate) and 5-fluorouracil in human plasma and urine using high-performance liquid chromatography and gas chromatography-negative ion chemical ionization mass spectrometry J Chromatogr B Biomed Sci Appl 691 95-104
  • [7] Saito K(2007)Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: four-arm cooperative study in Japan Ann Oncol 18 317-323
  • [8] Zergebel C(2009)Addition of S-1 to the epidermal growth factor receptor inhibitor gefitinib overcomes gefitinib resistance in non-small cell lung cancer cell lines with met amplification Clin Cancer Res 15 907-913
  • [9] Schiller J(2008)Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down-regulation of thymidylate synthase Mol Cancer Ther 7 599-606
  • [10] Hanna N(2002)Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer N Engl J Med 346 92-98