Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment

被引：7

作者：

Ahmet Algin

Marjolijn Wegdam-Blans

Kees Verduin

Hans Janssen

Jan-Melle van Dantzig

机构：

[1] Department of Cardiology, Catharina Hospital Eindhoven, Eindhoven 5623EJ

[2] Department of Microbiology, Catharina Hospital Eindhoven, Eindhoven 5623EJ

[3] Department of Microbiology, Sint Anna Hospital Geldrop, Geldrop 5664EH

[4] Department of Cardiology, Sint Anna Hospital Geldrop, Geldrop 5664EH

来源：

BMC Research Notes | / 5卷 / 1期

关键词：

Aortic valve; Endocarditis; Tropheryma whipplei;

D O I：

10.1186/1756-0500-5-600

中图分类号：

学科分类号：

摘要：

Background: Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue. Case presentation. In this case report, we described a patient with a classical Whipples disease. Transesophageal echocardiography (TEE) showed a vegetation on noncoronary cusp of the aortic valve. Whipples disease was confirmed by positive Tropheryma whipplei polymerase chain reaction (PCR) in EDTA blood and a duodenal biopsy with positive periodic acid-Schiff stain (PAS) macrophages. Conclusion: Due to timely diagnosis, our patient was treated with antibiotics without valve replacement. © 2012 Algin et al.; licensee BioMed Central Ltd.

引用

共 12 条

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