Biotransformation of oleic acid into (E)-10-hydroxy-8-octadecenoic acid and (E)-7,10-dihydroxy-8-octadecenoic acid by Pseudomonas sp. 42A2 in an immobilized system

被引:0
|
作者
J. Culleré
O. Durany
M. Busquets
A. Manresa
机构
[1] Facultat de Farmàcia,Laboratori di Microbiologia
来源
Biotechnology Letters | 2001年 / 23卷
关键词
biotransformation; hydroxy fatty acids; immobilisation; oleic acid;
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摘要
Oleic acid was transformed into 10-hydroxy-8E-octadecenoic acid and 7,10-dihydroxy-8E-octadecenoic acid using Pseudomonas sp. 42A2 NCIMB 40045 in different immobilised supports. Celite R633 gave highest conversions in 48 h: the cellular yield (Yp/x) g products g−1 of cellular protein in the immobilised culture was 5 compared with the free-cell culture Yp/x of 3.8. Conversion of oleic acid in the immobilised cell culture was 50% of the carbon source supplied.
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页码:215 / 219
页数:4
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