Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells

[1] Brittberg M(1994)Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation N Engl J Med 331 889-895

[2] Lindahl A(2000)Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee J Orthop Res 18 790-799

[3] Nilsson A(1977)Relationship between cell shape and type of collagen synthesized as chondrocytes lose their cartilage phenotype in culture Nature 267 531-532

[4] Ohlsson C(1988)Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture J Cell Sci 89 373-378

[5] Isaksson O(1999)Multilineage potential of adult human mesenchymal stem cells Science 284 143-147

[6] Peterson L(1998)Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow Tissue Eng 4 415-428

[7] Lee CR(2004)Chondrogenic differentiation of mesenchymal stem cells and its clinical applications Yonsei Med J 45 41-47

[8] Grodzinsky AJ(2002)In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis Proc Natl Acad Sci USA 99 4397-4402

[9] Hsu HP(2010)Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions J Orthop Res 28 834-840

[10] Martin SD(2012)Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation J Cell Physiol 227 88-97

[1] Brittberg M(1994)Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation N Engl J Med 331 889-895

[2] Lindahl A(2000)Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee J Orthop Res 18 790-799

[3] Nilsson A(1977)Relationship between cell shape and type of collagen synthesized as chondrocytes lose their cartilage phenotype in culture Nature 267 531-532

[4] Ohlsson C(1988)Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture J Cell Sci 89 373-378

[5] Isaksson O(1999)Multilineage potential of adult human mesenchymal stem cells Science 284 143-147

[6] Peterson L(1998)Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow Tissue Eng 4 415-428

[7] Lee CR(2004)Chondrogenic differentiation of mesenchymal stem cells and its clinical applications Yonsei Med J 45 41-47

[8] Grodzinsky AJ(2002)In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis Proc Natl Acad Sci USA 99 4397-4402

[9] Hsu HP(2010)Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions J Orthop Res 28 834-840

[10] Martin SD(2012)Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation J Cell Physiol 227 88-97