Inhibition of phosphorylated STAT3 by cucurbitacin I enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells

被引:0
作者
Charn-Jung Chang
Chih-Hung Chiang
Wen-Shin Song
Shen-Kou Tsai
Lin-Chung Woung
Chin-Hong Chang
Shaw-Yeu Jeng
Ching-Yao Tsai
Chuan-Chih Hsu
Hung-Fu Lee
Chi-Shuan Huang
Ming-Chi Yung
Jorn-Hon Liu
Kai-Hsi Lu
机构
[1] Tri-Service General Hospital and National Defense Medical Center,Department of Pharmacy Practice
[2] Cheng-Hsin General Hospital,Department of Surgery
[3] Cheng-Hsin General Hospital,Department of Medical Research and Education
[4] National Yang-Ming University,School of Medicine
[5] Taipei Veterans General Hospital—Su-Ao/Yuan-Shan Branch,Division of Urology, Department of Surgery
[6] Taipei City Hospital,Department of Ophthalmology
[7] Chi-Mei Medical Center,Department of Surgery
[8] Taiwan Adventist Hospital,Department of Surgery
来源
Child's Nervous System | 2012年 / 28卷
关键词
Medulloblastoma; Cucurbitacin I; Cancer stem cells; CD133; STAT3; Radioresistance;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:363 / 373
页数:10
相关论文
共 50 条
[21]   Glycomic and Transcriptomic Response of GSC11 Glioblastoma Stem Cells to STAT3 Phosphorylation Inhibition and Serum-Induced Differentiation [J].
He, Huan ;
Nilsson, Carol L. ;
Emmett, Mark R. ;
Marshall, Alan G. ;
Kroes, Roger A. ;
Moskal, Joseph R. ;
Ji, Yongjie ;
Colman, Howard ;
Priebe, Waldemar ;
Lang, Frederick F. ;
Conrad, Charles A. .
JOURNAL OF PROTEOME RESEARCH, 2010, 9 (05) :2098-2108
[22]   CD133 receptor mediated delivery of STAT3 inhibitor for simultaneous elimination of cancer cells and cancer stem cells in oral squamous cell carcinoma [J].
Pindiprolu, Sai Harshini ;
Pindiprolu, Sai Kiran S. S. .
MEDICAL HYPOTHESES, 2019, 129
[23]   Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition [J].
Ioanou, Nikolaos ;
Sedon, Alan M. ;
Dalgleish, Angus ;
Mackintosh, David ;
Solca, Flavio ;
Modjtahedi, Helmout .
INTERNATIONAL JOURNAL OF ONCOLOGY, 2016, 48 (03) :908-918
[24]   JAK/STAT3 and NF-κB Signaling Pathways Regulate Cancer Stem-Cell Properties in Anaplastic Thyroid Cancer Cells [J].
Shiraiwa, Ken ;
Matsuse, Michiko ;
Nakazawa, Yuka ;
Ogi, Tomoo ;
Suzuki, Keiji ;
Saenko, Vladimir ;
Xu, Shuhang ;
Umezawa, Kazuo ;
Yamashita, Shunichi ;
Tsukamoto, Kazuhiro ;
Mitsutake, Norisato .
THYROID, 2019, 29 (05) :674-682
[25]   IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer [J].
Bak, Yesol ;
Kwon, Taeho ;
Bak, In Seon ;
Hong, Jintae ;
Yu, Dae-Yeul ;
Yoon, Do-Young .
ONCOTARGET, 2016, 7 (06) :7307-7317
[26]   Inhibitory Effects of Tangeretin, a Citrus Peel-Derived Flavonoid, on Breast Cancer Stem Cell Formation through Suppression of Stat3 Signaling [J].
Ko, Yu-Chan ;
Choi, Hack Sun ;
Liu, Ren ;
Kim, Ji-Hyang ;
Kim, Su-Lim ;
Yun, Bong-Sik ;
Lee, Dong-Sun .
MOLECULES, 2020, 25 (11)
[27]   BMX-ARHGAP fusion protein maintains the tumorigenicity of gastric cancer stem cells by activating the JAK/STAT3 signaling pathway [J].
Xu, Xiao-Feng ;
Gao, Feng ;
Wang, Jian-Jiang ;
Long, Cong ;
Chen, Xing ;
Tao, Lan ;
Yang, Liu ;
Ding, Li ;
Ji, Yong .
CANCER CELL INTERNATIONAL, 2019, 19 (1)
[28]   STAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro [J].
Wang, Xiaoyan ;
Wang, Guozhu ;
Zhao, Yi ;
Liu, Xiaoan ;
Ding, Qiang ;
Shi, Jingping ;
Ding, Yin ;
Wang, Shui .
JOURNAL OF BIOMEDICAL RESEARCH, 2012, 26 (05) :325-335
[29]   STAT3 mediates resistance of CD44~+CD24-/low breast cancer stem cells to tamoxifen in vitro [J].
Xiaoyan Wanga ;
bLaboratory of Mesoscopic Chemistry and Department of Polymer Science and Engineering .
The Journal of Biomedical Research, 2012, (05) :325-335
[30]   BMX-ARHGAP fusion protein maintains the tumorigenicity of gastric cancer stem cells by activating the JAK/STAT3 signaling pathway [J].
Xiao-Feng Xu ;
Feng Gao ;
Jian-Jiang Wang ;
Cong Long ;
Xing Chen ;
Lan Tao ;
Liu Yang ;
Li Ding ;
Yong Ji .
Cancer Cell International, 19