Condensation of 2-aminomethylaniline with aldehydes and ketones for the fast one-pot synthesis of a library of 1,2,3,4-tetrahydroquinazolines under flow conditions

被引：0
|
作者：
Francesca Mangiavacchi
Leonardo Mollari
Luana Bagnoli
Francesca Marini
Claudio Santi
机构：
[1] University of Perugia,Department of Pharmaceutical Sciences, Group of Catalysis and Organic Green Chemistry
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
aldehydes; alumina; tetrahydroquinazoline; flow chemistry; green chemistry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new eco-friendly and reliable methodology for the synthesis of 1,2,3,4-tetrahydroquinazolines is proposed. This simple protocol was tested for the continuous synthesis of a small library of 1,2,3,4-tetrahydroquinazoline derivatives demonstrating good versatility and applicability.
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页码：478 / 481
页数：3
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