Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition

被引:0
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作者
Jie Zha
Feili Chen
Huijuan Dong
Pengcheng Shi
Yao Yao
Yanyan Zhang
Rongwei Li
Shiyun Wang
Peng Li
Weiguang Wang
Bing Xu
机构
[1] Southern Medical University,Department of Hematology, Nanfang Hospital
[2] Guangzhou Institutes of Biomedicine and Health,Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine
[3] Chinese Academy of Sciences,Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine
[4] South China Institute for Stem Cell Biology and Regenerative Medicine,Drug Discovery Pipeline
[5] Guangzhou Institutes of Biomedicine and Health,Research Institute in Healthcare Science, Faculty of Science and Engineering
[6] Chinese Academy of Sciences,undefined
[7] Guangzhou Institutes of Biomedicine and Health,undefined
[8] Chinese Academy of Sciences,undefined
[9] University of Wolverhampton,undefined
关键词
Disulfiram; Nrf2; NF-κB; JNK; Apoptosis;
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