Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition

被引：0
|
作者：
Jie Zha
Feili Chen
Huijuan Dong
Pengcheng Shi
Yao Yao
Yanyan Zhang
Rongwei Li
Shiyun Wang
Peng Li
Weiguang Wang
Bing Xu
机构：
[1] Southern Medical University,Department of Hematology, Nanfang Hospital
[2] Guangzhou Institutes of Biomedicine and Health,Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine
[3] Chinese Academy of Sciences,Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine
[4] South China Institute for Stem Cell Biology and Regenerative Medicine,Drug Discovery Pipeline
[5] Guangzhou Institutes of Biomedicine and Health,Research Institute in Healthcare Science, Faculty of Science and Engineering
[6] Chinese Academy of Sciences,undefined
[7] Guangzhou Institutes of Biomedicine and Health,undefined
[8] Chinese Academy of Sciences,undefined
[9] University of Wolverhampton,undefined
来源：
Journal of Translational Medicine | / 12卷
关键词：
Disulfiram; Nrf2; NF-κB; JNK; Apoptosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-κB pathway inhibition
    Zha, Jie
    Chen, Feili
    Dong, Huijuan
    Shi, Pengcheng
    Yao, Yao
    Zhang, Yanyan
    Li, Rongwei
    Wang, Shiyun
    Li, Peng
    Wang, Weiguang
    Xu, Bing
    JOURNAL OF TRANSLATIONAL MEDICINE, 2014, 12
  • [2] Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-kB and Nrf2
    Xu, Bing
    Wang, Shiyun
    Li, Rongwei
    Chen, Kai
    He, Lingli
    Deng, Manman
    Kannappan, Vinodh
    Zha, Jie
    Dong, Huijuan
    Wang, Weiguang
    CELL DEATH & DISEASE, 2017, 8 : e2797 - e2797
  • [3] Anticancer activity of Honokiol against lymphoid malignant cells via activation of ROS-JNK and attenuation of Nrf2 and NF-κB
    Gao, Da-Quan
    Qian, Shen-Xian
    Ju, Tong-Fa
    JOURNAL OF BUON, 2016, 21 (03): : 673 - 679
  • [4] Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway
    Li, Chang-ling
    Liu, Xiao-hong
    Qiao, Yun
    Ning, Lu-ning
    Li, Wen-jing
    Sun, Ying-shan
    Liu, De-shan
    Gao, Wei
    Ma, Chun-mei
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 876
  • [5] Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2
    Bing Xu
    Shiyun Wang
    Rongwei Li
    Kai Chen
    Lingli He
    Manman Deng
    Vinodh Kannappan
    Jie Zha
    Huijuan Dong
    Weiguang Wang
    Cell Death & Disease, 2017, 8 : e2797 - e2797
  • [6] Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-KB pathway
    Luo, Peng
    Huang, Qishan
    Chen, Suo
    Wang, Yinghui
    Dou, Haicheng
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 108
  • [7] DISULFIRAM/COPPER COMPLEX COULD ELIMINATE RAJI CELLS IN VITRO AND VIVO THROUGH ACTIVATION OF OXIDATIVE STRESS AND INHIBITION OF NRF2 AND NF-KB
    Xu, B.
    Zha, J.
    Chen, F.
    Shi, P.
    Guo, X.
    Wang, S.
    Li, R.
    Dong, H.
    HAEMATOLOGICA, 2013, 98 : 164 - 164
  • [8] Gnaq Protects PC12 Cells from Oxidative Damage by Activation of Nrf2 and Inhibition of NF-kB
    Xin Sun
    Guo-Ping Li
    Pu Huang
    Lu-Gang Wei
    Jia-Zhi Guo
    Li-Juan Ao
    Di Lu
    Shao-Chun Chen
    NeuroMolecular Medicine, 2020, 22 : 401 - 410
  • [9] Gnaq Protects PC12 Cells from Oxidative Damage by Activation of Nrf2 and Inhibition of NF-kB
    Sun, Xin
    Li, Guo-Ping
    Huang, Pu
    Wei, Lu-Gang
    Guo, Jia-Zhi
    Ao, Li-Juan
    Lu, Di
    Chen, Shao-Chun
    NEUROMOLECULAR MEDICINE, 2020, 22 (03) : 401 - 410
  • [10] Involvement of Nrf2 Activation and NF-kB Pathway Inhibition in the Antioxidant and Anti-Inflammatory Effects of Hesperetin in Activated BV-2 Microglial Cells
    Evans, Jasmine A.
    Mendonca, Patricia
    Soliman, Karam F. A.
    BRAIN SCIENCES, 2023, 13 (08)
12345