Procedure for quantitative determination of effectiveness of photoinduced destruction of malignant tumors

被引：0

作者：

Bizyuk S.A. ^{[1
]}

Istomin Yu.P. ^{[2
]}

Dzhagarov B.M. ^{[1
]}

机构：

[1] Institute of Molecular and Atomic Physics, National Academy of Sciences of Belarus, Minsk 220072

[2] N. N. Aleksandrov Scientific-Research Institute of Oncology and Medical Radiology, Minsk

来源：

Journal of Applied Spectroscopy | 2006年 / 73卷 / 4期

关键词：

Laser radiation; Photodynamic cancer therapy; Photoinduced reactions; Photosensitizer; Tumor necrosis;

D O I：

10.1007/s10812-006-0123-z

中图分类号：

学科分类号：

摘要：

We have developed a procedure for analysis of the functional status of blood vessels in tumor tissues using computer-assisted color scanning of tumor slices and also for a quantitative assessment of the effectiveness of photoinduced destruction of tumor tissues in animal experiments. Its major advantage is direct determination of the size of the tumor necrosis zone. The procedure has been tested in an experiment on three strains of malignant tumors with different morphologies. © 2006 Springer Science+Business Media, Inc.

引用

页码：588 / 592

页数：4

共 11 条

[1]

Yori G., Spikes J., J. Photochem. Photobiol. B: Biology, 6, pp. 93-101, (1990)

[2]

Busetti A., Soncin M., Reddi E., Rodgers M., Kenney M., Yori G., J. Photochem. Photobiol. B: Biology, 53, pp. 103-109, (1999)

[3]

Biziuk S.A., Dzhagarov B.M., Zhavrid E.A., Istomin Yu.P., Proceedings of Conference on Advanced Optoelectronics and Lasers, 1, pp. 288-291, (2005)

[4]

Dzhagarov B.M., Bizyuk S.A., Parkhats M.V., Zhavrid E.A., Istomin Yu.P., Proc. Int. Soc. for Opt. Eng., 5973, (2005)

[5]

Dzhagarov B.M., Bizyuk S.A., Parkhots M.V., Zhavrid E.A., Istomin Yu.P., Proceedings, Conference on Laser Optics Technology in Biology and Medicine, pp. 163-168, (2004)

[6]

Petrov P.T., Kaplan M.A., Istomin J.P., Proceedings, Fifth International Symposium on Photodynamic Diagnosis and Therapy in Clinical Practice, (2003)

[7]

Kostenich G.A., Photodynamic Therapy for Malignant Tumors, (1990)

[8]

Barun V.V., Ivanov A.P., Int. J. Heat and Mass Transfer, 46, pp. 3243-3254, (2003)

[9]

Vladimirov Yu.A., Potapenko A.Ya., Physicochemical Principles of Photobiological Processes [in Russian], (1989)

[10]

Barun V.V., Ivanov A.P., Dokl. NAN Belarusi, 49, pp. 48-52, (2005)

← 1 2 →