Structure-Guided Molecular Engineering of a Vascular Endothelial Growth Factor Antagonist to Treat Retinal Diseases

被引：0

作者：

Rakeeb Kureshi

Angela Zhu

Jikui Shen

Stephany Y. Tzeng

Leilani R. Astrab

Paul R. Sargunas

Jordan J. Green

Peter A. Campochiaro

Jamie B. Spangler

机构：

[1] Johns Hopkins University School of Medicine,Department of Biomedical Engineering

[2] Johns Hopkins University,Department of Chemical & Biomolecular Engineering

[3] Johns Hopkins University School of Medicine,Department of Ophthalmology, The Wilmer Eye Institute

[4] Johns Hopkins University School of Medicine,Department of Neuroscience

[5] Johns Hopkins University School of Medicine,Translational Tissue Engineering Center

[6] Johns Hopkins University,Insititute for Nanobiotechnology

[7] Johns Hopkins University,Department of Materials Science & Engineering

[8] Johns Hopkins University School of Medicine,Department of Neurosurgery

来源：

Cellular and Molecular Bioengineering | 2020年 / 13卷

关键词：

Ocular neovascularization; Vascular endothelial growth factor receptor; Directed evolution; Affinity engineering; Nonviral gene therapy;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：405 / 418

页数：13

共 13 条