Structure-Guided Molecular Engineering of a Vascular Endothelial Growth Factor Antagonist to Treat Retinal Diseases

被引：0
|
作者：
Rakeeb Kureshi
Angela Zhu
Jikui Shen
Stephany Y. Tzeng
Leilani R. Astrab
Paul R. Sargunas
Jordan J. Green
Peter A. Campochiaro
Jamie B. Spangler
机构：
[1] Johns Hopkins University School of Medicine,Department of Biomedical Engineering
[2] Johns Hopkins University,Department of Chemical & Biomolecular Engineering
[3] Johns Hopkins University School of Medicine,Department of Ophthalmology, The Wilmer Eye Institute
[4] Johns Hopkins University School of Medicine,Department of Neuroscience
[5] Johns Hopkins University School of Medicine,Translational Tissue Engineering Center
[6] Johns Hopkins University,Insititute for Nanobiotechnology
[7] Johns Hopkins University,Department of Materials Science & Engineering
[8] Johns Hopkins University School of Medicine,Department of Neurosurgery
来源：
Cellular and Molecular Bioengineering | 2020年 / 13卷
关键词：
Ocular neovascularization; Vascular endothelial growth factor receptor; Directed evolution; Affinity engineering; Nonviral gene therapy;
D O I：
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中图分类号：
学科分类号：
摘要：
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收藏
页码：405 / 418
页数：13
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