Secretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia colivia a modified Sec-dependent transporter construct

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作者
Sarah Förster
Manuela Brandt
Dorothea S Mottok
Anke Zschüttig
Kurt Zimmermann
Frederick R Blattner
Florian Gunzer
Christoph Pöhlmann
机构
[1] Institute of Medical Microbiology and Hygiene,Department of Genetics
[2] QIAGEN Hamburg GmbH,Department of Laboratory Medicine
[3] SymbioPharm GmbH,undefined
[4] Scarab Genomics LLC,undefined
[5] University of Wisconsin,undefined
[6] Robert-Bosch Hospital,undefined
来源
BMC Biotechnology | / 13卷
关键词
Interleukin-10; Outer membrane protein F; Inflammatory bowel disease; Bacterial transport system;
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[1]  
Ardizzone S(2005)Biologic therapy for inflammatory bowel disease Drugs 65 2253-2286
[2]  
Bianchi Porro G(2000)Treatment of murine colitis by Science 289 1352-1355
[3]  
Steidler L(2000) secreting interleukin-10 J Immunol 165 2783-2789
[4]  
Hans W(2009)Proinflammatory effects of IL-10 during human endotoxemia J Virol 83 9618-9629
[5]  
Schotte L(1998)Virus-encoded homologs of cellular interleukin-10 and their control of host immune function Trends Microbiol 6 190-197
[6]  
Neirynck S(2002)Immune evasion by cytomegalovirus–survival strategies of a highly adapted opportunist J Virol 76 1285-1292
[7]  
Obermeier F(2000)Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10 J Exp Med 191 213-224
[8]  
Falk W(2002)A single amino acid determines the immunostimulatory activity of interleukin 10 Cytokine 17 1-13
[9]  
Fiers W(2009)High level expression and purification of the Epstein-Barr virus encoded cytokine viral interleukin 10: efficient removal of endotoxin BMC Biotechnol 9 22-9
[10]  
Remaut E(2012)Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco J Mol Microbiol Biotechnol 22 1-9366