Recent advances in the genetics of attention deficit hyperactivity disorder

被引：20
作者：
Kent L. [1 ]
机构：
[1] Developmental Psychiatry Section, University of Cambridge, Cambridge CB2 2AH, Douglas House
来源：
Current Psychiatry Reports | 2004年 / 6卷 / 2期
关键词：
Attention Deficit Hyperactivity Disorder; Methylphenidate; Reading Disability; Attention Deficit Hyperactivity Disorder Symptom; COMT Gene;
D O I：
10.1007/s11920-004-0054-4
中图分类号：
学科分类号：
摘要：
In the past few years, interest in the molecular genetics of attention deficit hyperactivity disorder (ADHD) has grown enormously, with many groups searching for susceptibility genes, often through large collaborative efforts facilitated by the International ADHD Genetics Consortium, Association findings for several candidate genes within the dopaminergic system, the DRD4 and DRD5 receptor genes and the dopamine transporter gene, DAT1, have been well replicated, and the first of several ongoing genome linkage scan study results have been published. Current challenges in this field are to identify the actual functional variant(s) in these genes conferring susceptibility and other genetic and environmental risk factors for ADHD. Copyright © 2004 by Current Science Inc.
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页码：143 / 148
页数：5
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