VP22 and cytosine deaminase fusion gene modified tissue-engineered neural stem cells for glioma therapy

[1] Aboody KS(2008)Stem and progenitor cell-mediated tumor selective gene therapy Gene Ther 15 739-752

[2] Najbauer J(2011)Glioblastoma multiforme: can neural stem cells deliver the therapeutic payload and fulfill the clinical promise? Expert Rev Neurother 11 775-777

[3] Danks MK(2003)Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy Cancer Gene Ther 10 396-402

[4] Ahmed AU(2000)Gene therapy of experimental brain tumors using neural progenitor cells Nat Med 6 447-450

[5] Lesniak MS(2012)Stem cells as therapeutic vehicles for the treatment of high-grade gliomas Neuro Oncol 14 256-265

[6] Barresi V(1997)Intercellular trafficking and protein delivery by a herpesvirus structural protein Cell 88 223-233

[7] Belluardo N(1993)The “bystander effect”: tumor regression when a fraction of the tumor mass is genetically modified Cancer Res 53 5274-5283

[8] Sipione S(2005)Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival J Neurosci 25 2637-2646

[9] Mudo G(1994)Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase Proc Natl Acad Sci USA 91 8302-8306

[10] Cattaneo E(2008)Stable EGFP gene expression in C6 glioma cell line after transduction with HIV-1-based lentiviral vector Chin J Cancer Res 20 243-248

[1] Aboody KS(2008)Stem and progenitor cell-mediated tumor selective gene therapy Gene Ther 15 739-752

[2] Najbauer J(2011)Glioblastoma multiforme: can neural stem cells deliver the therapeutic payload and fulfill the clinical promise? Expert Rev Neurother 11 775-777

[3] Danks MK(2003)Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy Cancer Gene Ther 10 396-402

[4] Ahmed AU(2000)Gene therapy of experimental brain tumors using neural progenitor cells Nat Med 6 447-450

[5] Lesniak MS(2012)Stem cells as therapeutic vehicles for the treatment of high-grade gliomas Neuro Oncol 14 256-265

[6] Barresi V(1997)Intercellular trafficking and protein delivery by a herpesvirus structural protein Cell 88 223-233

[7] Belluardo N(1993)The “bystander effect”: tumor regression when a fraction of the tumor mass is genetically modified Cancer Res 53 5274-5283

[8] Sipione S(2005)Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival J Neurosci 25 2637-2646

[9] Mudo G(1994)Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase Proc Natl Acad Sci USA 91 8302-8306

[10] Cattaneo E(2008)Stable EGFP gene expression in C6 glioma cell line after transduction with HIV-1-based lentiviral vector Chin J Cancer Res 20 243-248