Solvent-free 1,3-dipolar cycloaddition of azomethine imines with terminal alkynes promoted by calcium fluoride under the ball milling condition

被引：0
|
作者：
Xianglong Chen
Chunman Jia
Li Cao
Dela Zhang
Shuixiang Liu
Qi Zhang
机构：
[1] Hainan University,Hainan Provincial Key Lab of Fine Chem
[2] Hainan University,Key Study Center of Ministry of Education for Tropical Resources Utilization
来源：
Chemical Research in Chinese Universities | 2015年 / 31卷
关键词：
Ball-milling; 1,3-Dipolar cycloaddition; Click chemistry; Solvent-free reaction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A convenient and efficient procedure for the synthesis of N,N-bicyclic pyrazolidinone derivatives has been developed via the reaction of azomethine imines with terminal alkynes under the ball milling condition without solvent, which was promoted by calcium fluoride with a catalyst of copper(I) salt. The cyclization reactions exhibited moderate to high yields.
引用
收藏
页码：543 / 548
页数：5
相关论文
共 17 条
  • [1] Solvent-free 1,3-Dipolar Cycloaddition of Azomethine Imines with Terminal Alkynes Promoted by Calcium Fluoride Under the Ball Milling Condition
    Chen Xianglong
    Jia Chunman
    Cao Li
    Zhang Dela
    Liu Shuixiang
    Zhang Qi
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 31 (04) : 543 - 548
  • [2] Unsupported Copper Nanoparticles in the 1,3-Dipolar Cycloaddition of Terminal Alkynes and Azides
    Alonso, Francisco
    Moglie, Yanina
    Radivoy, Gabriel
    Yus, Miguel
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 2010 (10) : 1875 - 1884
  • [3] A metal-organic framework as a highly efficient and reusable catalyst for the solvent-free 1,3-dipolar cycloaddition of organic azides to alkynes
    Li, Peng
    Regati, Sridhar
    Huang, Huicai
    Arman, Hadi D.
    Zhao, John C. -G.
    Chen, Banglin
    INORGANIC CHEMISTRY FRONTIERS, 2015, 2 (01): : 42 - 46
  • [4] Unsupported Copper Nanoparticles in the 1,3-Dipolar Cycloaddition of Terminal Alkynes and Azides (April, pg 1875, 2010)
    Alonso, Francisco
    Moglie, Yanina
    Radivoy, Gabriel
    Yus, Miguel
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 2010 (30) : 5913 - 5913
  • [5] And if everything was as easy as a "click". Cu(I)-catalyzed 1,3-dipolar cycloaddition between terminal alkynes and azides
    Lucas, Romain
    Zerrouki, Rachida
    Krausz, Pierre
    ACTUALITE CHIMIQUE, 2009, (335): : 5 - 9
  • [6] Ball Milling Assisted 1,3-Dipolar Cycloaddition Reaction of 1-(4-Nitrobenzyl)-pyridinium-3-olate
    Aboelnaga, Asmaa
    Abbady, Samia
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 27 (04) : 423 - 430
  • [7] Synthesis of new scaffolds of isoxazolidine derivatives from dihydrofuran via 1,3-dipolar cycloaddition reactions under solvent free conditions
    Chakraborty, Bhaskar
    Chettri, Esmita
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2018, 57 (12): : 1501 - 1508
  • [8] A Supported Copper Hydroxide on Titanium Oxide as an Efficient Reusable Heterogeneous Catalyst for 1,3-Dipolar Cycloaddition of Organic Azides to Terminal Alkynes
    Yamaguchi, Kazuya
    Oishi, Takamichi
    Katayama, Tatsuyori
    Mizuno, Noritaka
    CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (40) : 10464 - 10472
  • [9] A Supported Copper Hydroxide as an Efficient, Ligand-free, and Heterogeneous Precatalyst for 1,3-Dipolar Cycloadditions of Organic Azides to Terminal Alkynes
    Katayama, Tatsuyori
    Kamata, Keigo
    Yamaguchi, Kazuya
    Mizuno, Noritaka
    CHEMSUSCHEM, 2009, 2 (01) : 59 - 62
  • [10] An Efficient Copper-mediated 1,3-Dipolar Cycloaddition of Pyrazolidinone-based Dipoles to Terminal Alkynes to Produce N,N-Bicyclic Pyrazolidinone Derivatives
    Oishi, Takamichi
    Yoshimura, Kazuaki
    Yamaguchi, Kazuya
    Mizuno, Noritaka
    CHEMISTRY LETTERS, 2010, 39 (10) : 1086 - 1087
12