Microbial neoformation of volatiles: implications for the estimation of post-mortem interval in decomposed human remains in an indoor setting

被引：0
作者：
Ann-Sofie Ceciliason
M. Gunnar Andersson
Emma Lundin
Håkan Sandler
机构：
[1] Uppsala University,Forensic Medicine, Department of Surgical Sciences; Uppsala University Hospital
[2] The National Board of Forensic Medicine,Department of Forensic Medicine
[3] The National Veterinary Institute,Department of Chemistry, Environment and Feed Hygiene
来源：
International Journal of Legal Medicine | 2021年 / 135卷
关键词：
Neoformation of ethanol; N-Propanol; 1-Butanol; Acetaldehyde; Post-mortem interval; Total body score;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The objective of this study was to determine if a relationship between microbial neoformation of volatiles and the post-mortem interval (PMI) exists, and if the volatiles could be used as a tool to improve the precision of PMI estimation in decomposed human remains found in an indoor setting. Chromatograms from alcohol analysis (femoral vein blood) of 412 cases were retrospectively assessed for the presence of ethanol, N-propanol, 1-butanol, and acetaldehyde. The most common finding was acetaldehyde (83% of the cases), followed by ethanol (37%), N-propanol (21%), and 1-butanol (4%). A direct link between the volatiles and the PMI or the degree of decomposition was not observed. However, the decomposition had progressed faster in cases with microbial neoformation than in cases without signs of neoformation. Microbial neoformation may therefore act as an indicator of the decomposition rate within the early decomposition to bloating stages. This may be used in PMI estimation based on the total body score (TBS) and accumulated degree days (ADD) model, to potentially improve the model’s precision.
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页码：223 / 233
页数：10
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