Segmental Duplications in Subtelomeric Regions of Human Chromosome 13

被引：0
作者：
N. S. Kupriyanova
D. V. Shibalev
A. S. Voronov
O. V. Muravenko
A. V. Zelenin
A. P. Ryskov
机构：
[1] Russian Academy of Sciences,Institute of Gene Biology
[2] Russian Academy of Sciences,Engelhardt Institute of Molecular Biology
来源：
Molecular Biology | 2003年 / 37卷
关键词：
human chromosome 13; segmental duplication; subtelomeric and pericentric nucleotide sequences; ribosomal DNA; genome evolution;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Owing to a great progress in studying the human genome, its euchromatic portion is almost completely sequenced; the complete sequence is still unknown only for pericentric and telomeric regions and short arms of acrocentric chromosomes. Extended satellite blocks and segmental duplications located in these regions substantially hinder the joining of the sequenced fragments and construction of the full-length genome map. The sequence was established for a 1.5-kb human chromosome 13 subtelomeric region, which is about 10 kb away from the rDNA cluster, and deposited in GenBank under accession no. AF478540. The region showed 83–84% homology to the pericentric region of human chromosome 19, and contained short fragments homologous to the pericentric region of human chromosome 13. The results may contribute to the current revision of genome evolution concepts in view of numerous segmental duplications revealed.
引用
收藏
页码：194 / 199
页数：5
相关论文
共 50 条
[21]   Recent segmental and gene duplications in the mouse genome [J].
Joseph Cheung ;
Michael D Wilson ;
Junjun Zhang ;
Razi Khaja ;
Jeffrey R MacDonald ;
Henry HQ Heng ;
Ben F Koop ;
Stephen W Scherer .
Genome Biology, 4
[22]   An evolutionary driver of interspersed segmental duplications in primates [J].
Cantsilieris, Stuart ;
Sunkin, Susan M. ;
Johnson, Matthew E. ;
Anaclerio, Fabio ;
Huddleston, John ;
Baker, Carl ;
Dougherty, Max L. ;
Underwood, Jason G. ;
Sulovari, Arvis ;
Hsieh, PingHsun ;
Mao, Yafei ;
Catacchio, Claudia Rita ;
Malig, Maika ;
Welch, AnneMarie E. ;
Sorensen, Melanie ;
Munson, Katherine M. ;
Jiang, Weihong ;
Girirajan, Santhosh ;
Ventura, Mario ;
Lamb, Bruce T. ;
Conlon, Ronald A. ;
Eichler, Evan E. .
GENOME BIOLOGY, 2020, 21 (01)
[23]   The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements [J].
Tomàs Marques-Bonet ;
Ze Cheng ;
Xinwei She ;
Evan E Eichler ;
Arcadi Navarro .
BMC Genomics, 9
[24]   Interlocus gene conversion explains at least 2.7 % of single nucleotide variants in human segmental duplications [J].
Beth L. Dumont .
BMC Genomics, 16
[25]   Interlocus gene conversion explains at least 2.7 % of single nucleotide variants in human segmental duplications [J].
Dumont, Beth L. .
BMC GENOMICS, 2015, 16
[26]   Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence [J].
Joseph Cheung ;
Xavier Estivill ;
Razi Khaja ;
Jeffrey R MacDonald ;
Ken Lau ;
Lap-Chee Tsui ;
Stephen W Scherer .
Genome Biology, 4
[27]   The 200-kb segmental duplication on human chromosome 21 originates from a pericentromeric dissemination involving human chromosomes 2, 18 and 13 [J].
Golfier, G ;
Chibon, F ;
Aurias, A ;
Chen, XN ;
Korenberg, J ;
Rossier, J ;
Potier, MC .
GENE, 2003, 312 :51-59
[28]   Association of microsatellite pairs with segmental duplications in insect genomes [J].
Behura, Susanta K. ;
Severson, David W. .
BMC GENOMICS, 2013, 14
[29]   Segmental duplications and monosomies are linked to in vitro developmental arrest [J].
N. De Munck ;
A. Bayram ;
I. Elkhatib ;
A. Liñán ;
A. Arnanz ;
L. Melado ;
B. Lawrenz ;
M. H. Fatemi .
Journal of Assisted Reproduction and Genetics, 2021, 38 :2183-2192
[30]   Accelerated exon evolution within primate segmental duplications [J].
Belen Lorente-Galdos ;
Jonathan Bleyhl ;
Gabriel Santpere ;
Laura Vives ;
Oscar Ramírez ;
Jessica Hernandez ;
Roger Anglada ;
Gregory M Cooper ;
Arcadi Navarro ;
Evan E Eichler ;
Tomas Marques-Bonet .
Genome Biology, 14
12345