Vitamin D and calcium supplementation prevents severe falls in elderly community-dwelling women: A pragmatic population-based 3-year intervention study

被引:0
作者
Larsen E.R. [1 ]
Mosekilde L. [1 ]
Foldspang A. [2 ]
机构
[1] Department of Endocrinology and Metabolism, Aarhus University Hospital
[2] Institute of Epidemiology and Social Medicine, University of Aarhus, Aarhus
关键词
Accidental falls; Community; Home safety; Nutrition; Prevention; Vitamin D;
D O I
10.1007/BF03324585
中图分类号
学科分类号
摘要
Background and aims: We evaluated the effect of two programs for the prevention of falls leading to acute hospital admission in a population of elderly community-dwelling Danish residents. Methods: This was a factorial, pragmatic, intervention study. We included 9605 community-dwelling city residents aged 66+ years. We offered a prevention program consisting of a daily supplement of 1000 mg of elemental calcium as calcium carbonate and 400 IU (10 μg) of vitamin-D3 to a total of 4957 participants. The remaining 5063 participants were offered home safety inspection with dietary and health advice, or no intervention. Results: The Calcium and Vitamin D program was followed by 50.3% and the Environmental and Health Program by 46.4%. According to a multivariate analysis including age, marital status and intervention program, female residents who followed the Calcium and Vitamin D Program had a 12% risk reduction in severe falls (RR 0.88; 95% CI 0.79-0.98; p<0.05; NNT 9). Conclusions: The present study supports the hypothesis that vitamin D and calcium supplementation prevent falls leading to acute hospitalization in community-dwelling elderly females in a northern European region known to be deficient in vitamin D. ©2005, Editrice Kurtis.
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页码:125 / 132
页数:7
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