Drastically lowering the titer of waterborne bacteriophage PRD1 by exposure to immobilized hydrophobic polycations

被引:0
作者
Faina Gelman
Kim Lewis
Alexander M. Klibanov
机构
[1] Institute of Technology,Department of Chemistry and Division of Biological Engineering, Massachusetts
[2] Northeastern University,Department of Biology
来源
Biotechnology Letters | 2004年 / 26卷
关键词
adenoviruses; bacteriophage; detoxification; enteric; virus;
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学科分类号
摘要
Decrease in the titer of bacteriophage PRD1 (a model of animal adenoviruses) in aqueous solutions caused by the presence of systematically chemically derivatized surfaces was kinetically investigated. The greatest loss of infectivity – up to a 4-log reduction in the titer – was observed with immobilized hydrophobic polyethylenimine-based and dendrimer-based polycations.
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页码:1695 / 1700
页数:5
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