The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity

被引:0
作者
Monika Pruenster
Liesbeth Mudde
Paula Bombosi
Svetla Dimitrova
Marion Zsak
Jim Middleton
Ann Richmond
Gerard J Graham
Stephan Segerer
Robert J B Nibbs
Antal Rot
机构
[1] Experimental Pathology,Department of Veterans Affairs and Department of Cell Biology
[2] Novartis Institutes for BioMedical Research,Division of Immunology
[3] Medical School,undefined
[4] Keele University,undefined
[5] Robert Jones & Agnes Hunt Orthopaedic Hospital,undefined
[6] Vanderbilt University School of Medicine,undefined
[7] Infection and Inflammation,undefined
[8] Glasgow Biomedical Research Centre,undefined
[9] University of Glasgow,undefined
[10] Medizinische Poliklinik,undefined
[11] University of Munich,undefined
[12] Clinic for Nephrology,undefined
[13] University of Zurich,undefined
[14] Zurich CH-8091,undefined
[15] Switzerland.,undefined
来源
Nature Immunology | 2009年 / 10卷
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中图分类号
学科分类号
摘要
Nonsignaling chemokine receptors are thought to function as chemokine 'decoys'. Rot and colleagues now show that the nonsignaling chemokine receptor DARC functions to unidirectionally transport inflammatory chemokines toward apical endothelial surfaces.
引用
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页码:101 / 108
页数:7
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