Differential diagnosis of idiopathic inflammatory myopathies

被引：19
作者：
Baer A.N. [1 ]
机构：
[1] Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14215
来源：
Current Rheumatology Reports | 2006年 / 8卷 / 3期
关键词：
Myopathy; Muscular Dystrophy; Muscle Biopsy; Myositis; Spinal Muscular Atrophy;
D O I：
10.1007/s11926-996-0023-5
中图分类号：
学科分类号：
摘要：
Symmetric proximal muscle weakness has many potential etiologies. An onset over weeks to months and elevated serum levels of muscle enzymes point to the diagnosis of an idiopathic inflammatory myopathy, including dermatomyositis, polymyositis, and inclusion body myositis. However, there is a broad differential diagnosis, including certain muscular dystrophies, metabolic myopathies, drug- or toxin-induced myotoxicity, neuropathies, and infectious myositides. The differentiation is critical for defining appropriate treatment. In addition, an alternative diagnosis may explain the lack of response to immunosuppressive treatment for some patients with polymyositis. Careful clinical evaluation and choice of available diagnostic tests are required to establish the correct diagnosis. Copyright © 2006 by Current Science Inc.
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页码：178 / 187
页数：9
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