Unusual exanthema combined with cerebral vasculitis in pneumococcal meningitis: A case report

被引：3

作者：

Tavladaki T. ^{[1
]}

Spanaki A.-M. ^{[1
]}

Ilia S. ^{[1
]}

Geromarkaki E. ^{[1
]}

Raissaki M. ^{[2
]}

Briassoulis G. ^{[1
]}

机构：

[1] Paediatric Intensive Care Unit, University Hospital of Heraklion, University of Crete, Heraklion, Crete

[2] Department of Radiology, University Hospital of Heraklion, University of Crete, Heraklion, Crete

来源：

Journal of Medical Case Reports | / 5卷 / 1期

关键词：

Meningitis; Bacterial Meningitis; Invasive Pneumococcal Disease; Pneumococcal Meningitis; Pneumococcal Conjugate Vaccine;

D O I：

10.1186/1752-1947-5-410

中图分类号：

学科分类号：

摘要：

Introduction. Bacterial meningitis is a complex, rapidly progressive disease in which neurological injury is caused in part by the causative organism and in part by the host's own inflammatory responses. Case presentation. We present the case of a two-year-old Greek girl with pneumococcal meningitis and an atypical curvilinear-like skin eruption, chronologically associated with cerebral vasculitis. A diffusion-weighted MRI scan showed lesions with restricted diffusion, reflecting local areas of immunologically mediated necrotizing vasculitis. Conclusions: Atypical presentations of bacterial meningitis may occur, and they can be accompanied by serious unexpected complications. © 2011 Tavladaki et al; licensee BioMed Central Ltd.

引用

共 15 条

[1]

Vergouwen M.D., Schut E.S., Troost D., Van De Beek D., Diffuse cerebral intravascular coagulation and cerebral infarction in pneumococcal meningitis, Neurocrit Care, 13, pp. 217-227, (2010)

[2]

Scheld W.M., Koedel U., Nathan B., Pfister H.-W., Pathophysiology of bacterial meningitis: Mechanism(s) of neuronal injury, J Infect Dis, 186, SUPPL. 2, pp. 19225-233, (2002)

[3]

Vestrheim D.F., Hoiby E.A., Bergsaker M.R., Ronning K., Aaberge I.S., Caugant D.A., Indirect effect of conjugate pneumococcal vaccination in a 2+1 dose schedule, Vaccine, 28, pp. 2214-2221, (2010)

[4]

Harboe Z.B., Valentiner-Branth P., Benfield T.L., Christensen J.J., Andersen P.H., Howitz M., Krogfelt K.A., Lambertsen L., Konradsen H.B., Early effectiveness of heptavalent conjugate pneumococcal vaccination on invasive pneumococcal disease after the introduction in the Danish Childhood Immunization Programme, Vaccine, 28, pp. 2642-2647, (2010)

[5]

Fisher J.D., Insidious presentation of pediatric pneumococcal meningitis: Alive and well in the post vaccine era, Am J Emerg Med, 27, (2009)

[6]

Sundelof B., Gnarpe H., Gnarpe J., An unusual manifestation of chlamydia pneumoniae infection: Meningitis, hepatitis, iritis and atypical erythema nodosum, Scandinavian Journal of Infectious Diseases, 25, 2, pp. 259-261, (1993)

[7]

Karanika M., Vasilopoulou V.A., Katsioulis A.T., Papastergiou P., Theodoridou M.N., Hadjichristodoulou C.S., Diagnostic clinical and laboratory findings in response to predetermining bacterial pathogen: Data from the Meningitis Registry, PLoS One, 4, (2009)

[8]

Kutz J.W., Simon L.M., Chennupati S.K., Giannoni C.M., Manolidis S., Clinical predictors for hearing loss in children with bacterial meningitis, Archives of Otolaryngology - Head and Neck Surgery, 132, 9, pp. 941-945, (2006)

[9]

Worsoe L., Caye-Thomasen P., Brandt C.T., Thomsen J., Stergaard C., Factors associated with the occurrence of hearing loss after pneumococcal meningitis, Clin Infect Dis, 51, pp. 917-924, (2010)

[10]

Jorens P.G., Parizel P.M., Demey H.E., Smets K., Jadoul K., Verbeek M.M., Wevers R.A., Cras P., Meningoencephalitis caused by Streptococcus pneumoniae: A diagnostic and therapeutic challenge. Diagnosis with diffusion-weighted MRI leading to treatment with corticosteroids, Neuroradiology, 47, 10, pp. 758-764, (2005)

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