A New Synthesis of Calcium N-(5-Hydroxynicotinoyl)-L-glutamate and Its X-ray Diffraction Structure

被引：0
|
作者：
A. V. Kiselev
A. A. Machula
S. I. Efimov
E. B. Pashkova
S. V. Stovbun
机构：
[1] Russian Academy of Sciences,Semenov Institute of Chemical Physics
[2] All-Russian Research Institute of Agricultural Radiology and Agroecology,BION
来源：
Russian Journal of Organic Chemistry | 2019年 / 55卷
关键词：
Ampasse; calcium ; -(5-hydroxynicotinoyl)-L-glutamate; -(5-hydroxynicotinoyl)-L-glutamic acid; 5-hydroxynicotinic acid; diethyl L-glutamate; XRD;
D O I：
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中图分类号：
学科分类号：
摘要：
A new synthesis of N-(5-hydroxynicotinoyl)-L-glutamic acid via a 5-hydroxynicotinic acid imidazolide intermediate has been developed. Its calcium salt (Ampasse) has been synthesized and its structure was studied by X-ray diffraction analysis. The reaction conditions for all stages of the process have been optimized and a method for the purification of the substance has been improved.
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页码：615 / 619
页数：4
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