A 49-year-old woman presented with severe swelling and pain of the left little finger, which had exacerbated rapidly, in October 2006. The patient had a history of hepatocellular carcinoma and metastatic lung cancer. She had undergone partial hepatectomy for the hepatocellular carcinoma in September 2001 and pulmonary resection for metastatic lung cancer in November 2005. Roentgenogram of the hand on admission showed complete destruction of the distal phalanx of the left little finger. The final pathological result of the tissue obtained by disarticulation was an extrahepatic metastasis of hepatocellular carcinoma. Extrahepatic metastasis from primary hepatocellular carcinoma to the hand is very rare and only four cases have been reported in the literature. All the patients with extrahepatic metastases from the primary hepatocellular carcinoma to the hand had poor prognoses, but the patient presented in this article exhibited an unusual clinical course. The patient is still alive 1 year after the diagnosis of extrahepatic bone metastasis of the distal phalanx.
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Fdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Florimonte, Luigia
Iavarone, Massimo
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Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, M & MA Migliavacca Ctr Liver Dis, Milan, Italy
Univ Milan, Div Gastroenterol & Hepatol, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Iavarone, Massimo
Castellani, Massimo
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Fdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Castellani, Massimo
Longo, Mariagiulia
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Univ Milan, Dept Hlth Sci, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Longo, Mariagiulia
Pallotti, Francesco
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Fdn IRCCS Ca Granda Osped Maggiore Policlin, Div Pathol, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Pallotti, Francesco
Maffioli, Lorenzo
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ASST Ovest Milanese Osped Legnano, Nucl Med & Multihosp Oncol Dept, Legnano, MI, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Maffioli, Lorenzo
Orunesu, Eva
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Fdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy
Orunesu, Eva
Benti, Riccardo
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Fdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, ItalyFdn IRCCS Ca Granda Osped Maggiore Policlin, Nucl Med Dept, Granelli Bldg,Via Francesco Sforza 35, Milan, Italy