Whole-body MR-DWIBS vs. [18F]-FDG-PET/CT in the study of malignant tumors: a retrospective study

被引:16
作者
Cafagna, D. [2 ]
Rubini, G. [1 ]
Iuele, F. [1 ]
Maggialetti, N. [3 ]
Notaristefano, A. [1 ]
Pinto, D. [2 ]
Niccoli-Asabella, A. [1 ]
Palmiotti, G. [4 ]
Lasciarrea, M.
Maggialetti, A. [5 ]
机构
[1] Univ Bari, Nucl Med Unit, Di MIMP, I-70124 Bari, Italy
[2] Ricerche Radiol, Molfetta, Italy
[3] Univ Bari, DIMIMP, I-70124 Bari, Italy
[4] Di Venere Hosp, Oncol Unit, Bari, Italy
[5] L Bonomo Hosp, Radiol Unit, Andria, Italy
来源
RADIOLOGIA MEDICA | 2012年 / 117卷 / 02期
关键词
DWIBS; F-18]-FDG-PET/CT; ADC; SUV; Malignant tumour; Glucose metabolism; MAGNETIC-RESONANCE; DIFFUSION; ONCOLOGY; PET; LESIONS;
D O I
10.1007/s11547-011-0708-3
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose. Our aim was to assess the overall diagnostic accuracy of magnetic resonance diffusion-weighted whole-body imaging with background signal suppression (MR-DWIBS) compared with ([F-18]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT), considered the reference standard of whole-body tumour imaging modalities, in a series of consecutive patients with malignant tumour. Materials and methods. Thirty-eight patients diagnosed with a malignant tumour over a 4-month period were enrolled in this retrospective, observational study. PET/CT and MR-DWIBS images were reviewed in double-blind manner by a nuclear medicine physician and radiologists with 4 years experience. Lesion size, standard uptake value (SUV) and apparent diffusion coefficient (ADC) were measured and calculated for each lesion. Results. The qualitative analysis of MR-DWIBS and [F-18]-FDG-PET/CT showed that two patients were negative at both techniques. MR-DWIBS was positive in 36 patients, 34 of whom were positive and two negative at [F-18]-FDG-PET/CT, respectively. Two hundred and fifty-five lesions were identified by MR-DWIBS and 184 by [F-18]-FDG-PET/CT, which was a significative discordance. Correlation between SUV and ADC of lesions positive at both techniques was not statistically significant. The mean difference between lesion size in [F-18]-FDG-PET/CT and MR-DWIBS was not statistically significant. No correlation was found between glucose metabolism and water motion. Conclusions. MR-DWIBS may be used to evaluate localisation of parenchymal neoplasms but is less efficacious in characterising lymph-node and skeletal lesions. [F-18]-FDG-PET/CT remains the best whole-body technique to identify lymph-node and skeletal lesions, but its limitation is identifying tumours with low glucose metabolism as in mucinous neoplasms. MR-DWIBS evaluation must be integrated with morphological images to increase MR diagnostic accuracy.
引用
收藏
页码:293 / 311
页数:19
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