LncRNA OTUD6B-AS1 overexpression promoted GPX4-mediated ferroptosis to suppress radioresistance in colorectal cancer

被引：0
作者：
Zilang Zhang
Baolong Ye
Yiban Lin
Wenjun Liu
Jianzhong Deng
Wu Ji
机构：
[1] Southern Medical University,Department of General Surgery, Jinling Hospital, the First School of Clinical Medicine
[2] The First People’s Hospital of Foshan,Department of Anorectal Surgery
[3] The Third Affiliated Hospital of Guangzhou Medical University,Department of General Surgery
来源：
Clinical and Translational Oncology | 2023年 / 25卷
关键词：
Colorectal cancer; Ferroptosis; Radiation resistance; OTUD6B-AS1; TRIM16;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：3217 / 3229
页数：12
相关论文
共 50 条
  • [21] α-Hederin causes ferroptosis in triple-negative breast cancer through modulating IRF1 to suppress GPX4
    Wu, Xue
    Jin, Lingli
    Ren, Disuo
    Huang, Shaolong
    Meng, Xinyu
    Wu, Zhixuan
    Lv, Chaoyue
    Ru, Jiatong
    Zhang, Heyu
    Zhang, Shuwei
    Bao, Jingxia
    Wang, Ouchen
    Xia, Erjie
    PHYTOMEDICINE, 2025, 141
  • [22] Lens epithelium cell ferroptosis mediated by m6A-lncRNA and GPX4 expression in lens tissue of age-related cataract
    Yong Wang
    Pengfei Li
    Congyu Wang
    Sijie Bao
    Siwen Wang
    Guowei Zhang
    Xi Zou
    Jian Wu
    Yu Guan
    Min Ji
    Huaijin Guan
    BMC Ophthalmology, 23
  • [23] RETRACTED: Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation (Retracted Article)
    Shen, Lian-Dong
    Qi, Wen-Hai
    Bai, Jiang-Jiang
    Zuo, Chun-Yi
    Bai, Dong-Lin
    Gao, Wei-Dong
    Zong, Xin-Ling
    Hao, Ting-Ting
    Ma, Yan
    Cao, Guang-Cai
    ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 2021, 304 (02): : 313 - 322
  • [24] Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation
    Shen, Zhennv
    Zhao, Lei
    Yoo, Seung-ah
    Lin, Zhenhua
    Zhang, Yu
    Yang, Wenqing
    Piao, Junjie
    APOPTOSIS, 2024, 29 (9-10) : 1810 - 1823
  • [25] Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer
    Zeng, Kaixuan
    Li, Weihao
    Wang, Yue
    Zhang, Zifei
    Zhang, Linjie
    Zhang, Weili
    Xing, Yue
    Zhou, Chi
    ADVANCED SCIENCE, 2023, 10 (25)
  • [26] Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer
    Feng, Shengjie
    Rao, Zejun
    Zhang, Jiakun
    She, Xiaowei
    Chen, Yaqi
    Wan, Kairui
    Li, Haijie
    Zhao, Chongchong
    Feng, Yongdong
    Wang, Guihua
    Hu, Junbo
    Luo, Xuelai
    ADVANCED SCIENCE, 2023, 10 (36)
  • [27] IRF1 suppresses colon cancer proliferation by reducing SPI1-mediated transcriptional activation of GPX4 and promoting ferroptosis
    Chen, Yilin
    Lin, Beian
    Yang, Shiyu
    Huang, Jingshan
    EXPERIMENTAL CELL RESEARCH, 2023, 431 (01)
  • [28] Luteolin exhibits synergistic therapeutic efficacy with erastin to induce ferroptosis in colon cancer cells through the HIC1-mediated inhibition of GPX4 expression
    Zheng, Yinli
    Li, Leyan
    Chen, Haipeng
    Zheng, Yuting
    Tan, Xuanjing
    Zhang, Guiyu
    Jiang, Ruidi
    Yu, Hong
    Lin, Senyi
    Wei, Yijie
    Wang, Ying
    Zhang, Rong
    Liu, Zhongqiu
    Wu, Jinjun
    FREE RADICAL BIOLOGY AND MEDICINE, 2023, 208 : 530 - 544
  • [29] In vitro siRNA-mediated GPX4 and AKT1 silencing in oxaliplatin resistance cancer cells induces ferroptosis and apoptosis
    Golbashirzadeh, Morteza
    Heidari, Hamid Reza
    Aghamolayi, Ali Asghar
    Fattahi, Yasin
    Talebi, Mehdi
    Khosroushahi, Ahmad Yari
    MEDICAL ONCOLOGY, 2023, 40 (10)
  • [30] In vitro siRNA-mediated GPX4 and AKT1 silencing in oxaliplatin resistance cancer cells induces ferroptosis and apoptosis
    Morteza Golbashirzadeh
    Hamid Reza Heidari
    Ali Asghar Aghamolayi
    Yasin Fattahi
    Mehdi Talebi
    Ahmad Yari Khosroushahi
    Medical Oncology, 40
12345