Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

被引：0

作者：

Neelroop N. Parikshak

Vivek Swarup

T. Grant Belgard

Manuel Irimia

Gokul Ramaswami

Michael J. Gandal

Christopher Hartl

Virpi Leppa

Luis de la Torre Ubieta

Jerry Huang

Jennifer K. Lowe

Benjamin J. Blencowe

Steve Horvath

Daniel H. Geschwind

机构：

[1] Center for Autism Research and Treatment and Program in Neurobehavioral Genetics,Department of Neurology

[2] Semel Institute,Department of Molecular Genetics

[3] David Geffen School of Medicine,Department of Human Genetics

[4] University of California,Department of Biostatistics

[5] Los Angeles,undefined

[6] David Geffen School of Medicine,undefined

[7] University of California Los Angeles,undefined

[8] Centre for Genomic Regulation,undefined

[9] Barcelona Institute of Science and Technology (BIST),undefined

[10] Universitat Pompeu Fabra (UPF),undefined

[11] Donnelly Centre,undefined

[12] University of Toronto,undefined

[13] University of Toronto,undefined

[14] David Geffen School of Medicine,undefined

[15] University of California,undefined

[16] David Geffen School of Medicine,undefined

[17] University of California,undefined

来源：

Nature | 2016年 / 540卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Gene expression analysis in brain tissue from individuals with and without autism spectrum disorder (ASD) suggests that the transcription factor SOX5 contributes to an ASD-associated reduction in transcriptional differences between brain areas and indicates that common transcriptomic changes occur in different forms of ASD.

引用

页码：423 / 427

页数：4

共 100 条

[81]

Leek JT(undefined)undefined undefined undefined undefined-undefined

[82]

Storey JD(undefined)undefined undefined undefined undefined-undefined

[83]

Love MI(undefined)undefined undefined undefined undefined-undefined

[84]

Huber W(undefined)undefined undefined undefined undefined-undefined

[85]

Anders S(undefined)undefined undefined undefined undefined-undefined

[86]

Friedman J(undefined)undefined undefined undefined undefined-undefined

[87]

Hastie T(undefined)undefined undefined undefined undefined-undefined

[88]

Tibshirani R(undefined)undefined undefined undefined undefined-undefined

[89]

Dittmar KA(undefined)undefined undefined undefined undefined-undefined

[90]

Kang HJ(undefined)undefined undefined undefined undefined-undefined

← 1 2 3 4 5 6 7 8 9 10 →