Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders

被引：0
作者：
Elina Jokiranta-Olkoniemi
David Gyllenberg
Dan Sucksdorff
Auli Suominen
Kim Kronström
Roshan Chudal
Andre Sourander
机构：
[1] University of Turku and Turku University Hospital,Department of Child Psychiatry
[2] University of Helsinki and Helsinki University Central Hospital,Department of Adolescent Psychiatry
[3] National Institute of Health and Welfare,Department of Adolescent Psychiatry
[4] University of Turku and Turku University Hospital,INVEST Research Flagship Center
[5] University of Turku,undefined
来源：
Journal of Autism and Developmental Disorders | 2021年 / 51卷
关键词：
Autism; Mortality; Suicide; Psychiatric disorders; Natural cause;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders.
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页码：3098 / 3108
页数：10
相关论文
共 159 条
  • [1] Amiet C(2008)Epilepsy in autism is associated with intellectual disability and gender: Evidence from a meta-analysis Biological Psychiatry 64 577-582
  • [2] Gourfinkel-An I(2013)Excess mortality and causes of death in autism spectrum disorders: A follow up of the 1980s Utah/UCLA autism epidemiologic study Journal of Autism and Developmental Disorders 43 1196-1204
  • [3] Bouzamondo A(2014)Suicidal ideation and suicide plans or attempts in adults with asperger's syndrome attending a specialist diagnostic clinic: A clinical cohort study Lancet Psychiatry 1 142-147
  • [4] Tordjman S(2017)Risk of suicide attempts among adolescents and young adults with autism spectrum disorder: A nationwide longitudinal follow-up study The Journal of Clinical Psychiatry 78 e1174-e1179
  • [5] Baulac M(2002)Descriptive epidemiology of autism in a california population: Who is at risk? Journal of Autism and Developmental Disorders 32 217-224
  • [6] Lechat P(2018)Autistic traits and suicidal thoughts, plans, and self-harm in late adolescence: population-based cohort study Journal of the American Academy of Child and Adolescent Psychiatry 57 313-320
  • [7] Mottron L(2010)Mortality in autism: A prospective longitudinal community-based study Journal of Autism and Developmental Disorders 40 352-357
  • [8] Cohen D(2016)Premature mortality in autism spectrum disorder The British Journal of Psychiatry 208 232-238
  • [9] Bilder D(1999)Mortality and causes of death in pervasive developmental disorders Autism 3 7-16
  • [10] Botts EL(2016)Demographic characteristics and psychiatric comorbidity of children and adolescents diagnosed with ADHD in specialized healthcare Child Psychiatry and Human Development 47 574-582
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