Endoplasmic reticulum: Membrane contact sites

被引：0
作者：
Velikanov G.A. [1 ]
机构：
[1] Kazan Institute of Biochemistry and Biophysics, Kazan Research Center of the Russian Academy of Sciences, Kazan
来源：
Cell and Tissue Biology | 2013年 / 7卷 / 6期
关键词：
endoplasmic reticulum; functions; membrane contact sites;
D O I：
10.1134/S1990519X13060138
中图分类号：
学科分类号：
摘要：
This paper presents a review of modern data on the functional designation of membrane contact sites (MCSs) of endoplasmic reticulum. Problems of traffic of lipids and calcium in are discussed. It is to be emphasized that the function of MCSs is not yet clear, while the mechanism providing contact of two membranes (the problem of "anchors") remains poorly studied. Data are discussed that testify in favor of MCSs being able to participate both in selective traffic of lipids and in free diffusion of any small molecule (apparently, up to 1.5 kDa) and ions between cell compartments that are in contact. © 2013 Pleiades Publishing, Ltd.
引用
收藏
页码：504 / 511
页数：7
相关论文
共 78 条
[51]  
Simmen, T., Aslan, J.E., Blagoveshchenskaya, A.D., Thomas, L., Wan, L., Xiang, Y., Feliciangeli, S.F., Thomas, G., PACS-2 controls endoplasmic reticulum-mitochondria communication and Bidmediated apoptosis (2005) EMBO J., 24, pp. 717-729
[52]  
Sleight, R.G., Pagano, R.E., Rapid appearance of newly synthesized phosphatidylethanolamine at the plasma membrane (1983) J. Biol. Chem., 258, pp. 9050-9058
[53]  
Staehelin, L.A., The plant ER: a dynamic organelle composed of a large number of discrete functional domains (1997) Plant, J11, pp. 1151-1165
[54]  
Stefan, C.J., Manford, A.G., Baird, D., Yamada-Hanff, J., Mao, Y., Emr, S.D., Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites (2011) Cell, 144, pp. 389-401
[55]  
Takeshima, H., Komazaki, S., Nishi, M., Iino, M., Kangava, K., Junctophilins: a novel family of junctional membrane complex proteins (2000) Mol. Cell., 6, pp. 11-22
[56]  
Terasaki, M., Slater, N.T., Fein, A., Schmidek, A., Reese, T.S., Continuous network of endoplasmic reticulum in cerebellar Purkinje neurons (1994) Proc. Natl. Acad. Sci. USA, 91, pp. 7510-7514
[57]  
Terent'ev, A.A., Moldogazieva, N.T., Shaitan, K.V., Dynamic Proteomics in living cell modeling (2009) Usp. Biol. Khim., 49, pp. 429-480
[58]  
Toulmay, A., Prinz, W.A., Lipid transfer and signaling at organelle contact sites: the tip of the iceberg (2011) Curr. Opin. Cell Biol., 23, pp. 458-463
[59]  
Tsujishita, Y., Hurley, J.H., Structure and lipid transport mechanism of a StAR-related domain (2000) Nat. Struct. Biol., 7, pp. 408-414
[60]  
Vance, J.E., Molecular and cell biology of phosphatidylserine and phosphatidylethanolamine metabolism (2003) Prog. Nucleic Acid Res. Mol. Biol., 75, pp. 69-111
12345678