Metformin mediated reversal of epithelial to mesenchymal transition is triggered by epigenetic changes in E-cadherin promoter

被引:0
|
作者
Poulomi Banerjee
Harshini Surendran
Debabani Roy Chowdhury
Karthik Prabhakar
Rajarshi Pal
机构
[1] Manipal University,School of Regenerative Medicine
[2] Manipal Hospital,Department of Diabetes and Endocrinology
[3] Functional Genomics and Gene Silencing Group,undefined
[4] Centre for Cellular and Molecular Biology,undefined
来源
关键词
Epithelial-mesenchymal transition; Metformin; Diabetes; ERK; AMPK; E-cadherin; Methylation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1397 / 1409
页数:12
相关论文
共 50 条
  • [1] Metformin mediated reversal of epithelial to mesenchymal transition is triggered by epigenetic changes in E-cadherin promoter
    Banerjee, Poulomi
    Surendran, Harshini
    Chowdhury, Debabani Roy
    Prabhakar, Karthik
    Pal, Rajarshi
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2016, 94 (12): : 1397 - 1409
  • [2] Eribulin affects E-cadherin localization consistent with a reversal of the epithelial-to-mesenchymal transition
    Dybdal-Hargreaves, N. F.
    Rohena, C. C.
    Risinger, A. L.
    Mooberry, S. L.
    CANCER RESEARCH, 2016, 76
  • [3] E-cadherin on epithelial–mesenchymal transition in thyroid cancer
    Xiaoyu Zhu
    Xiaoping Wang
    Yifei Gong
    Junlin Deng
    Cancer Cell International, 21
  • [4] Epigenetic Analysis of E-cadherin and Epithelial to Mesenchymal Transition in Primary And Metastatic Lung Cancer Cells
    Buckingham, L.
    Barbanera, W.
    Escarzaga, D.
    Fidler, M.
    Bonomi, P.
    JOURNAL OF THORACIC ONCOLOGY, 2012, 7 (09) : S246 - S246
  • [5] Small molecule mediated transcriptional derepression of E-cadherin and inhibition of epithelial to mesenchymal transition
    An, Hanbing
    Deane, Natasha
    Stoops, Sydney
    Zhu, Jing
    Waterson, Alex
    Zijlstra, Andries
    Lindsley, Craig
    Beauchamp, Robert Daniel
    CANCER RESEARCH, 2015, 75
  • [6] E-cadherin on epithelial-mesenchymal transition in thyroid cancer
    Zhu, Xiaoyu
    Wang, Xiaoping
    Gong, Yifei
    Deng, Junlin
    CANCER CELL INTERNATIONAL, 2021, 21 (01)
  • [7] E-cadherin to N-cadherin switching in the TGF-β1 mediated retinal pigment epithelial to mesenchymal transition
    Wei, Jiayi
    Wu, Liangjing
    Yang, Shuai
    Zhang, Conghui
    Feng, Le
    Wang, Minli
    Li, Hui
    Wang, Fang
    EXPERIMENTAL EYE RESEARCH, 2022, 220
  • [8] A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition
    Kumar, Sanjeev
    Park, Sun Hee
    Cieply, Benjamin
    Schupp, Jane
    Killiam, Elizabeth
    Zhang, Fan
    Rimm, David L.
    Frisch, Steven M.
    MOLECULAR AND CELLULAR BIOLOGY, 2011, 31 (19) : 4036 - 4051
  • [9] Tuberin Regulates E-Cadherin Localization Implications in Epithelial-Mesenchymal Transition
    Barnes, Elizabeth A.
    Kenerson, Heidi L.
    Jiang, Xiuyun
    Yeung, Raymond S.
    AMERICAN JOURNAL OF PATHOLOGY, 2010, 177 (04): : 1765 - 1778
  • [10] Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer
    Hollestelle, Antoinette
    Peeters, Justine K.
    Smid, Marcel
    Timmermans, Mieke
    Verhoog, Leon C.
    Westenend, Pieter J.
    Heine, Anouk A. J.
    Chan, Alan
    Sieuwerts, Anieta M.
    Wiemer, Erik A. C.
    Klijn, Jan G. M.
    van der Spek, Peter J.
    Foekens, John A.
    Schutte, Mieke
    den Bakker, Michael A.
    Martens, John W. M.
    BREAST CANCER RESEARCH AND TREATMENT, 2013, 138 (01) : 47 - 57