共 160 条
[1]
Ni D(2019)Drugging K-RasG12C through covalent inhibitors: mission possible? Pharmacol Ther 202 1-7
[2]
Li X(2020)Targeting Krasg12c-mutant cancer with a mutation-specific inhibitor J Intern Med 288 183-191
[3]
He X(1989)Ras oncogenes in human cancer: a review Cancer Res 49 4682-4689
[4]
Zhang H(2017)RAS proteins and their regulators in human disease Cell 170 17-33
[5]
Zhang J(2014)Drugging the undruggable RAS: mission possible? Nat Rev Drug Discov 13 828-851
[6]
Lu S(2017)Drugging RAS: know the enemy Science 355 1158-1163
[7]
Christensen JG(2016)Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design Nat Rev Drug Discov 15 771-1546
[8]
Olson P(2015)Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations J Proteome Res 14 1535-1753
[9]
Briere T(2016)Outcome according to KRAS-, NRAS-and BRAF-mutation as well as KRAS mutation variants: pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group Ann Oncol 27 1746-225
[10]
Wiel C(2020)KRAS G12C metastatic colorectal cancer: specific features of a new emerging target population Clin Colorectal Cancer 19 219-929