Polymorphism of Promotor Sites of Interleukins-4 and -10 and Tumor Necrosis Factor-alpha Genes in HIV-Infected Patients

被引：0
作者：
V. I. Konenkov
M. V. Smol'nikova
机构：
[1] Siberian Branch of Russian Academy of Medical Sciences,Institute of Clinical Immunology
来源：
Bulletin of Experimental Biology and Medicine | 2002年 / 133卷
关键词：
interleukins; tumor necrosis factor-alpha; gene polymorphism; HIV infection; Russian population;
D O I：
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中图分类号：
学科分类号：
摘要：
The distribution of allele variants of promotor sites of interleukins 4 (C-590T) and 10 (C-597A) and tumor necrosis factor-alpha (G-308A) genes was studied in HIV-infected patients and normal subjects of the Europeoid population in Russia. Some deviations in the distribution of genotypes of the studied polymorphism were revealed in HIV-infected patients compared to the control. The distribution of genotypes in these groups is different for men and women, which is significant for inheritance of allele variants of the cytokine gene.
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页码：389 / 391
页数：2
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