Effect of fluoride toothpastes on enamel demineralization

被引:32
作者
Arnold W.H. [1 ]
Dorow A. [1 ]
Langenhorst S. [1 ]
Gintner Z. [2 ]
Bánóczy J. [2 ]
Gaengler P. [1 ]
机构
[1] Faculty of Dental Medicine, University of Witten/Herdecke, Witten
[2] Faculty of Dentistry, Semmelweis University, Budapest
关键词
Enamel Surface; Polarization Light Microscopy; Control Window; Enamel Demineralization; Fluoride Compound;
D O I
10.1186/1472-6831-6-8
中图分类号
学科分类号
摘要
Background: It was the aim of this study to investigate the effect of four different toothpastes with differing fluoride compounds on enamel remineralization. Methods: A 3 x 3 mm window on the enamel surface of 90 human premolars was demineralized in a hydroxyethylcellulose solution at pH 4.8. The teeth were divided into 6 groups and the lower half of the window was covered with varnish serving as control. The teeth were immersed in a toothpaste slurry containing: placebo tooth paste (group 1); remineralization solution (group 2); Elmex Anticaries (group 3); Elmex Sensitive (group 4); Blend-a-med Complete (group 5) and Colgate GRF (group 6). Ten teeth of each group were used for the determination of the F- content in the superficial enamel layer and acid solubility of enamel expressed in soluble phosphorus. Of 6 teeth of each group serial sections were cut and investigated with polarization light microscopy (PLM) and quantitative energy dispersive X-ray analysis (EDX). Results: The PLM results showed an increased remineralization of the lesion body in the Elmex Anticaries, Elmex Sensitive and Colgate GRF group but not in the Blend-a-med group. A statistically significant higher Ca content was found in the Elmex Anticaries group. The fluoride content in the superficial enamel layer was significantly increased in both Elmex groups and the Blend-a-med group. Phosphorus solubility was significantly decreased in both Elmex groups and the Blend-a-med group. Conclusion: It can be concluded that amine fluoride compounds in toothpastes result in a clearly marked remineralization of caries like enamel lesions followed by sodium fluoride and sodium monofluorophosphate formulations. © 2006 Arnold et al; licensee BioMed Central Ltd.
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