Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors

Amaravadi RK(2011)Principles and current strategies for targeting autophagy for cancer treatment Clin Cancer Res 17 654-666

Lippincott-Schwartz J(2005)Lysosomes and autophagy in cell death control Nat Rev Cancer 5 886-897

Yin X-MXM(2005)Growth factor regulation of autophagy and cell survival in the absence of apoptosis Cell 120 237-248

Weiss WA(2014)Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma J Clin Invest. 124 1406-1417

Takebe N(2010)Mammalian autophagy: core molecular machinery and signaling regulation Curr Opin Cell Biol. 22 124-131

Timmer W(2016)Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy? Cancer Cell Int 16 62-1424

Kroemer G(2016)Autophagy is associated with chemoresistance in neuroblastoma BMC Cancer. 16 891-116

Jäättelä M(2012)EGFR tyrosine kinase inhibition induces autophagy in cancer cells Cancer Biol Ther 13 1417-448

Lum JJ(2016)Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature Crit Rev Oncol Hematol. 100 107-181

Bauer DE(2018)TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy Eur J Pharmacol. 818 435-886

Amaravadi RK(2011)Principles and current strategies for targeting autophagy for cancer treatment Clin Cancer Res 17 654-666

Lippincott-Schwartz J(2005)Lysosomes and autophagy in cell death control Nat Rev Cancer 5 886-897

Yin X-MXM(2005)Growth factor regulation of autophagy and cell survival in the absence of apoptosis Cell 120 237-248

Weiss WA(2014)Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma J Clin Invest. 124 1406-1417

Takebe N(2010)Mammalian autophagy: core molecular machinery and signaling regulation Curr Opin Cell Biol. 22 124-131

Timmer W(2016)Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy? Cancer Cell Int 16 62-1424

Kroemer G(2016)Autophagy is associated with chemoresistance in neuroblastoma BMC Cancer. 16 891-116

Jäättelä M(2012)EGFR tyrosine kinase inhibition induces autophagy in cancer cells Cancer Biol Ther 13 1417-448

Lum JJ(2016)Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature Crit Rev Oncol Hematol. 100 107-181

Bauer DE(2018)TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy Eur J Pharmacol. 818 435-886