Anaplastic large cell lymphoma (monomorphic post-transplant lymphoproliferative disorder) presenting in gallbladder

被引：0

作者：

Wey E.A. ^{[1
]}

Smith L.B. ^{[1
]}

机构：

[1] Department of Pathology, University of Michigan, Ann Arbor, MI 48109

来源：

Journal of Hematopathology | 2011年 / 4卷 / 1期

关键词：

Anaplastic large cell lymphoma; Gallbladder; Lung transplant; Post-transplant lymphoproliferative disorder;

D O I：

10.1007/s12308-010-0080-6

中图分类号：

学科分类号：

摘要：

Primary lymphomas of the gallbladder are rare, particularly in the post-transplant setting. Post-transplant lymphoproliferative disorder (PTLD) is a well-described complication of the immunosuppressive therapy employed post-transplant and manifests as a broad spectrum of disease ranging from polymorphic lymphoid proliferations to monomorphic lymphomas. The majority of PTLD consists of B-cell proliferations, although a small subset involves T-cell neoplasms. Of T-cell PTLD, anaplastic large cell lymphoma (ALCL) is a rare subtype. Of note, there are no reported cases of ALCL localized to the gallbladder in either the post-transplant setting or otherwise. We report a case of ALCL (monomorphic PTLD) in a 45-year-old male lung transplant recipient. Within the first year post-transplant, the patient presented with sepsis and acalculous cholecystitis. The patient ultimately underwent an open cholecystectomy and was subsequently found to have ALCL of the gallbladder. Despite aggressive treatment of septic shock, renal failure, and coagulopathy, the patient died 5 days after presentation. © 2010 Springer-Verlag.

引用

页码：17 / 20

页数：3

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