Glutamate-induced disturbances in neurotransmission and ionic homeostasis of extracellular Ca2+ and K+ in CA1 hippocampal area

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作者：
V. G. Motin
机构：
[1] Russian Academy of Medical Sciences,P. K. Anokhin institute of Nornal Physiology
来源：
Bulletin of Experimental Biology and Medicine | 1997年 / 124卷
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摘要：
The effect of various concentrations ofl-glutamate on neurotransmission in the CA1 hippocampal area was studied using hippocampal slices. Three intervals ofl-glutamate concentration were established: ≤1 mM (all studied parameters are completely reversible upon washout, transmission being preserved), from 1 to 10 mM (both responses to frequency stimulation and single population spikes remain partially suppressed after washout), and above 10 mM (more than 50% suppression of transmission persists after washout).
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页码：844 / 847
页数：3
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