Chemical Pathways of Peptide Degradation. X: Effect of Metal-Catalyzed Oxidation on the Solution Structure of a Histidine-Containing Peptide Fragment of Human Relaxin

被引：0
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作者：
Mehrnaz Khossravi
Ronald T. Borchardt
机构：
[1] The University of Kansas,Department of Pharmaceutical Chemistry
[2] The University of Kansas,Department of Pharmaceutical Chemistry
来源：
Pharmaceutical Research | 2000年 / 17卷
关键词：
ascorbate; cupric chloride; histidine; metal-catalyzed oxidation;
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摘要：
Purpose. To elucidate the major degradation products of the metal-catalyzedoxidation of (cyclo S-S) AcCys-Ala-X-Val-Gly-CysNH2(X = His, cyclic-His peptide), which is a fragment of the proteinrelaxin, and the effect of this oxidation on its solution structure.
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页码：851 / 858
页数：7
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