3D-printed microchip electrophoresis device containing spiral electrodes for integrated capacitively coupled contactless conductivity detection

被引:0
作者
Brenda M. C. Costa
Aline G. Coelho
Michael J. Beauchamp
Jacob B. Nielsen
Gregory P. Nordin
Adam T. Woolley
José A. F. da Silva
机构
[1] Chemistry Institute,Department of Chemistry and Biochemistry
[2] State University of Campinas,Department of Electrical and Computer Engineering
[3] Brigham Young University,undefined
[4] Brigham Young University,undefined
[5] Instituto Nacional de Ciência e Tecnologia em Bioanalítica (INCTBio),undefined
来源
Analytical and Bioanalytical Chemistry | 2022年 / 414卷
关键词
Liquid metal electrodes; Microchip electrophoresis; 3D printing;
D O I
暂无
中图分类号
学科分类号
摘要
In this work, we demonstrate for the first time the design and fabrication of microchip electrophoresis devices containing cross-shaped channels and spiral electrodes around the separation channel for microchip electrophoresis and capacitively coupled contactless conductivity detection. The whole device was prepared in a digital light processing–based 3D printer in poly(ethylene glycol) diacrylate resin. Outstanding X-Y resolution of the customized 3D printer ensured the fabrication of 40-μm cross section channels. The spiral channels were filled with melted gallium to form conductive electrodes around the separation channel. We demonstrate the applicability of the device on the separation of sodium, potassium, and lithium cations by microchip electrophoresis.
引用
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页码:545 / 550
页数:5
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[1]  
Ngo TD(2018)Additive manufacturing (3D printing): a review of materials, methods, applications and challenges Composites Part B 143 172-196
[2]  
Kashania A(2016)3D printed microfluidic devices: enablers and barriers Lab Chip 16 1993-2013
[3]  
Imbalzano G(2011)Let there be chip—towards rapid prototyping of microfluidic devices: one-step manufacturing processes Anal Methods 3 2681-2716
[4]  
Nguyen KTQ(2017)Comparing microfluidic performance of three-dimensional (3D) printing platforms Anal Chem 89 3858-3866
[5]  
Hui D(2017)Fused Deposition modeling 3D printing for (bio)analytical device fabrication: procedures, materials, and applications Anal Chem 89 7053-7061
[6]  
Waheed S(2019)A simple procedure to produce FDM-based 3D-printed microfluidic devices with an integrated PMMA optical window Anal Methods 11 1014-1020
[7]  
Cabot JM(2020)3D printed microfluidics Annu Rev Anal Chem 13 1.1-1.21
[8]  
Macdonald NP(2015)Optical approach to resin formulation for 3D printed microfluidics RSC Adv 5 106621-106632
[9]  
Lewis T(2017)Moving from millifluidic to truly microfluidic sub-100-μm cross-section 3D printed devices Anal Bioanal Chem 409 4311-4319
[10]  
Guijt RM(2017)Custom 3D printer and resin for 18 μm × 20 μm microfluidic flow channels Lab Chip 17 2899-2909