Efficacy of silver treated catheters for haemodialysis in preventing bacterial adhesion

被引:0
作者
F. Paladini
M. Pollini
A. Talà
P. Alifano
A. Sannino
机构
[1] University of Salento,Department of Engineering for Innovation
[2] University of Salento,Department of Biological and Environmental Sciences and Technologies
来源
Journal of Materials Science: Materials in Medicine | 2012年 / 23卷
关键词
Silver Nanoparticles; Inductively Couple Plasma Atomic Emission Spectroscopy; Simulated Body Fluid; Bacterial Adhesion; Inductively Couple Plasma Atomic Emission Spectroscopy;
D O I
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中图分类号
学科分类号
摘要
The growing resistance of many strains of bacteria to antibiotics and antiseptics is becoming a serious problem in medicine. Nano-silver is one of the most prominent products in medicine because it exhibits unusual physicochemical properties and a strong biological activity. In this work an innovative silver deposition technology was applied to temporary polyurethane catheters for haemodialysis. The working conditions of catheters were reproduced through laboratory equipment that ensured the flow of deionized water and simulated body fluid inside the lumina at corporeal temperature. The growth and the adhesion of Staphylococcus aureus on the surface of the device were studied through fluorescence microscopy. ICP-AES was adopted to calculate the amount of silver released from the substrate. The stability of the coating during the whole working life of the device was demonstrated through thermo-gravimetric analysis.
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页码:1983 / 1990
页数:7
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