The Interaction Between Levofloxacine Hydrochloride and DNA Mediated by Cu2+

被引：0
|
作者：
Gongwu Song
Yu He
Zhaoxia Cai
机构：
[1] Hubei University,Faculty of Chemistry and Material Science
来源：
Journal of Fluorescence | 2004年 / 14卷
关键词：
Levofloxacin; DNA; Cu; fluorescence;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Levofloxacin (LEV) is a fluoroquinolone antimicrobial agent. LEV also inhibits DNA synthesis and is bactericidal. The mechanisms of the interaction among LEV, DNA and Cu2+ are studied by fluorescence method. In the paper, the results show that LEV and Cu2+ can form binary complex, and also LEV and DNA can form complex mediated by Cu2+. The composition of the complex is determined. The affects to the reaction are also found.
引用
收藏
页码：705 / 710
页数：5
相关论文
共 50 条
  • [41] Interaction between ciprofloxacin and DNA mediated by Mg2+-ions
    Skauge, T
    Turel, I
    Sletten, E
    INORGANICA CHIMICA ACTA, 2002, 339 : 239 - 247
  • [42] The effect of Cu2+ on the interaction between an antitumor drug-mitoxantrone and human serum albumin
    Tian, Ming-Yue
    Zhang, Xiu-Feng
    Xie, Ling
    Xiang, Jun-Feng
    Tang, Ya-Lin
    Zhao, Chang-Qi
    JOURNAL OF MOLECULAR STRUCTURE, 2008, 892 (1-3) : 20 - 24
  • [43] Interaction between adenine and Cu2+ and Fe3+-montmorillonites: a prebiotic chemistry experiment
    Pereira, Rodrigo C.
    Teixeira, Bruna S.
    da Costa, Antonio C. S.
    Zaia, Dimas A. M.
    INTERNATIONAL JOURNAL OF ASTROBIOLOGY, 2021, 20 (03) : 223 - 233
  • [44] Evaluation of Interaction Between Histidine Binding Cu2+ Ion and Histidine by Atomic Force Microscopy
    Kim, Jong Min
    Lee, Haeng-Ja
    Kim, Woo-Sik
    Sano, Masato
    Muramatsu, Hiroshi
    Chang, Sang-Mok
    JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2012, 12 (07) : 5164 - 5167
  • [45] Study of Cu2+ mediated oxidation of thiosemicarbazide, thiocarbohydrazide and thiourea
    Chattopadhyay, SK
    Mak, TCW
    INORGANIC CHEMISTRY COMMUNICATIONS, 2000, 3 (03) : 111 - 113
  • [46] Side Effect of Tris on the Interaction of Amyloid β-peptide with Cu2+: Evidence for Tris-Aβ-Cu2+ Ternary Complex Formation
    Bin, Yannan
    Jiang, Zhongxiu
    Xiang, Juan
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2015, 176 (01) : 56 - 65
  • [47] Interaction between bovine serum albumin and umbelliferone with/without metal ions of Cu2+ or Zn2+
    Liu, Xue-Feng
    Xia, Yong-Mei
    Fang, Yun
    Zou, Lu
    Liu, Ling-Ling
    Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis, 2005, 25 (08): : 1301 - 1305
  • [48] Interaction between bovine serum albumin and umbelliferone with/without metal ions of Cu2+ or Zn2+
    Liu, XF
    Xia, YM
    Fang, Y
    Zou, L
    Liu, LL
    SPECTROSCOPY AND SPECTRAL ANALYSIS, 2005, 25 (08) : 1301 - 1305
  • [49] CONFIGURATION INTERACTION SCREENING FACTORS FOR CU2+ IN CRYSTAL FIELDS
    LOWTHER, JE
    JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS, 1974, 35 (08) : 917 - 919
  • [50] STUDIES ON THE INTERACTION OF POLY (I-C) WITH CU2+
    YANG, P
    HUA, EB
    YANG, BS
    ZONG, JC
    CHINESE SCIENCE BULLETIN, 1993, 38 (20): : 1717 - 1721
12345