The Interaction Between Levofloxacine Hydrochloride and DNA Mediated by Cu2+

被引：0
|
作者：
Gongwu Song
Yu He
Zhaoxia Cai
机构：
[1] Hubei University,Faculty of Chemistry and Material Science
来源：
Journal of Fluorescence | 2004年 / 14卷
关键词：
Levofloxacin; DNA; Cu; fluorescence;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Levofloxacin (LEV) is a fluoroquinolone antimicrobial agent. LEV also inhibits DNA synthesis and is bactericidal. The mechanisms of the interaction among LEV, DNA and Cu2+ are studied by fluorescence method. In the paper, the results show that LEV and Cu2+ can form binary complex, and also LEV and DNA can form complex mediated by Cu2+. The composition of the complex is determined. The affects to the reaction are also found.
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页码：705 / 710
页数：5
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