Mangiferin exerts neuroprotective effects against focal cerebral ischemia in mice by regulating NF-κB signaling pathway

被引:0
|
作者
Tianpao Hao
Chan Chen
Shen Yang
Yang Zhang
Feiyu Liang
机构
[1] The First Affiliated Hospital of Wenzhou Medical University,Department of Emergency
[2] The First Affiliated Hospital of Wenzhou Medical University,Department of Geriatric Medicine
[3] Wuhu NO.1 People’s Hospital,Departments of Neurology
[4] The First Affiliated Hospital of Wenzhou Medical University,Department of Neurology
来源
Metabolic Brain Disease | 2023年 / 38卷
关键词
Mangiferin; NF-κB signaling pathway; Focal cerebral ischemia; Neuroinflammation;
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中图分类号
学科分类号
摘要
Purpose: Mangiferin is a natural free radical scavenging antioxidant that induces excitation of the central nervous system. However, the mechanism of neuroprotective effect of mangiferin on focal cerebral ischemia has not been fully investigated. The aim of this study was to investigate the protective effect of mangiferin on focal cerebral ischemia in mice.
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页码:383 / 391
页数:8
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