The association between body size, prostate volume and prostate-specific antigen

被引：0
作者：
J H Fowke
S S Motley
M S Cookson
R Concepcion
S S Chang
M L Wills
J A Smith
机构：
[1] Vanderbilt Epidemiology Center,Division of Internal Medicine and Public Health
[2] Vanderbilt University Medical Center,Department of Urologic Surgery
[3] Vanderbilt University Medical Center,Department of Pathology
[4] Urology Associates,undefined
[5] Vanderbilt University Medical Center,undefined
来源：
Prostate Cancer and Prostatic Diseases | 2007年 / 10卷
关键词：
obesity; prostate volume; height; PSA; benign prostatic hyperplasia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Increasing prostate volume contributes to urinary tract symptoms and may obscure prostate cancer detection. We investigated the association between obesity and prostate volume, prostate-specific antigen (PSA) and PSA density among 753 men referred for prostate biopsy. Among men with a negative biopsy, prostate volume significantly increased approximately 25% from the lowest to highest body mass index (BMI), waist or hip circumference or height categories. PSA was 0.7 ng/ml lower with a high waist-to-hip ratio. These associations were less consistent among subjects diagnosed with high-grade prostatic intraepithelial neoplasia or cancer. Our data suggest that obesity and height are independently associated with prostate volume.
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页码：137 / 142
页数：5
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