Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer’s disease

[41] DeStefano AL(2014)From endosomes to the trans-Golgi network Semin Cell Dev Biol 31 30-15311

[42] Gudnason V(2011)The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM Cell 147 1118-250

[43] Boada M(2012)siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat J Controll Release 161 132-1635

[44] Bis JC(1994)Evidence that production and release of amyloid beta-protein involves the endocytic pathway J Biol Chem 269 17386-11709

[45] Smith AV(2001)Nucleocytoplasmic shuttling of endocytic proteins J Cell Biol 153 1511-26334

[46] Carassquillo MM(2015)Modulation of PICALM levels perturbs cellular cholesterol homeostasis PLoS One 10 e0129776-408

[47] Lambert JC(2013)Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer’s APP-CTF for terminal degradation via autophagy Proc Natl Acad Sci USA 110 17071-390

[48] Hardy J(2012)Role of genes linked to sporadic Alzheimer’s disease risk in the production of beta-amyloid peptides Proc Natl Acad Sci USA 109 15307-178

[49] Allsop D(2009)The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide Biochem Biophys Res Commun 385 247-1061

[50] Koo EH(2010)Alzheimer’s-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition Proc Natl Acad Sci USA 107 1630-undefined

[41] DeStefano AL(2014)From endosomes to the trans-Golgi network Semin Cell Dev Biol 31 30-15311

[42] Gudnason V(2011)The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM Cell 147 1118-250

[43] Boada M(2012)siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat J Controll Release 161 132-1635

[44] Bis JC(1994)Evidence that production and release of amyloid beta-protein involves the endocytic pathway J Biol Chem 269 17386-11709

[45] Smith AV(2001)Nucleocytoplasmic shuttling of endocytic proteins J Cell Biol 153 1511-26334

[46] Carassquillo MM(2015)Modulation of PICALM levels perturbs cellular cholesterol homeostasis PLoS One 10 e0129776-408

[47] Lambert JC(2013)Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer’s APP-CTF for terminal degradation via autophagy Proc Natl Acad Sci USA 110 17071-390

[48] Hardy J(2012)Role of genes linked to sporadic Alzheimer’s disease risk in the production of beta-amyloid peptides Proc Natl Acad Sci USA 109 15307-178

[49] Allsop D(2009)The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide Biochem Biophys Res Commun 385 247-1061

[50] Koo EH(2010)Alzheimer’s-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition Proc Natl Acad Sci USA 107 1630-undefined